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B cell-derived cytokines in disease*
Centre de Pharmacologie & Innovation dans le Diabète FRE 3400 CNRS Montpellier France
* Corresponding Author: P. Guglielmi,
European Cytokine Network 2013, 24(1), 20-26. https://doi.org/10.1684/ecn.2013.0327
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B cells regulate immune responses during infectious, inflammatory and autoimmune diseases. Beside their unique and characteristic antibody production, B lymphocytes can modulate physiological and pathological processes by presenting antigens or synthesizing signaling molecules. In human and mouse diseases, immunointervention, targeting B cells, has revealed and highlighted their antibody-independent regulatory contribution. In this review, we focus on B cell-cytokine production, which is commonly disturbed in inflammatory disorders, and describe the B cell cytokine profile in different diseases. Finally, we discuss some key issues for future B cell-targeted therapies.Keywords
B lymphocyte, autoimmunity, inflammation, cancer
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APA Style
Hamze, M., Desmetz, C., Guglielmi, P. (2013). B cell-derived cytokines in disease*. European Cytokine Network, 24(1), 20–26. https://doi.org/10.1684/ecn.2013.0327
Vancouver Style
Hamze M, Desmetz C, Guglielmi P. B cell-derived cytokines in disease*. Eur Cytokine Network. 2013;24(1):20–26. https://doi.org/10.1684/ecn.2013.0327
IEEE Style
M. Hamze, C. Desmetz, and P. Guglielmi, “B cell-derived cytokines in disease*,” Eur. Cytokine Network, vol. 24, no. 1, pp. 20–26, 2013. https://doi.org/10.1684/ecn.2013.0327
Copyright © 2013 The Author(s). Published by Tech Science Press.This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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