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Proteogenomics for pediatric brain cancer


University of Californian Los Angeles, David Geffen School of Medicine, Los Angeles, 90095, USA

* Corresponding Author: MARGARET SIMONIAN. Email:

BIOCELL 2021, 45(6), 1459-1463.


Pediatric central nervous system tumors are the most common tumors in children, it constitute 15%–20% of all malignancies in children and are the leading cause of cancer related deaths in children. Proteogenomics is an emerging field of biological research that utilizes a combination of proteomics, genomics, and transcriptomics to aid in the discovery and identification of biomarkers for diagnosis and therapeutic purposes. Integrative proteogenomics analysis of pediatric tumors identified underlying biological processes and potential treatments as well as the functional effects of somatic mutations and copy number variation driving tumorigenesis.


Cite This Article

SIMONIAN, M. (2021). Proteogenomics for pediatric brain cancer. BIOCELL, 45(6), 1459–1463.

This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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