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Apigenin as a promising myocyte protectant against damage and degradation

XIAO HUANG1,2,3,#,*, ZHIHAI YU4,#, LIJUAN NING5, YU LEI5, XUEFEI ZHANG5, ZHUYING WANG2,*

1 Institute of Cultural and Technological Industry Innovation of Tongren, Tongren, 554300, China
2 School of Sports and Physical Education, Nanjing Normal University, Nanjing, 210046, China
3 School of Physical Education, Guangxi University of Science and Technology, Liuzhou, 545006, China
4 Department of Urology Surgery, Chongqing University Three Gorges Hospital, Chongqing, 404000, China
5 School of Sports and Health Science, Tongren University, Tongren, 554300, China
# These two authors contribute equally to this work

* Corresponding Authors: XIAO HUANG, email; ZHUYING WANG, email

BIOCELL 2022, 46(2), 383-388. https://doi.org/10.32604/biocell.2021.015651

Abstract

Myocytes power the movement of all organs in the body. Damage to and degradation of myocytes causes hypokinesia and muscle-related degenerative diseases. Apigenin, a kind of flavone, is being used to treat many disorders. It exerts a host of different pharmacological activities, such as anti-inflammatory, anti-mutagenic, cardioprotective, and antioxidant effects. Accordingly, apigenin is considered a promising candidate for myocyte protection. In this review, we introduced the characteristics of apigenin. The means of apigenin protection of myocytes as well as the mechanism were summarized and discussed. The protective effects can be classified into proliferation-promoting, anti-inflammatory, atrophy-preventing, metabolism-increasing, and antioxidative effects. Additionally, we provided some outlook on the valuable applications of apigenin in sports medicine, which eagerly require further fundamental research.

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APA Style
HUANG, X., YU, Z., NING, L., LEI, Y., ZHANG, X. et al. (2022). Apigenin as a promising myocyte protectant against damage and degradation. BIOCELL, 46(2), 383-388. https://doi.org/10.32604/biocell.2021.015651
Vancouver Style
HUANG X, YU Z, NING L, LEI Y, ZHANG X, WANG Z. Apigenin as a promising myocyte protectant against damage and degradation. BIOCELL . 2022;46(2):383-388 https://doi.org/10.32604/biocell.2021.015651
IEEE Style
X. HUANG, Z. YU, L. NING, Y. LEI, X. ZHANG, and Z. WANG "Apigenin as a promising myocyte protectant against damage and degradation," BIOCELL , vol. 46, no. 2, pp. 383-388. 2022. https://doi.org/10.32604/biocell.2021.015651



cc This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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