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From organ-on-a-chip towards body-on-a-chip

JONG HWAN SUNG*
Hongik University, Seoul, 04066, Korea
* Address correspondence to: Jong Hwan Sung,

BIOCELL 2022, 46(5), 1177-1180. https://doi.org/10.32604/biocell.2022.019055

Received 31 August 2021; Accepted 13 December 2021; Issue published 06 January 2022

Abstract

Organ-on-a-chip technology aims to reproduce the key physiological features of human organs and tissues, even complex actions of multi-organ interaction. While organ-on-a-chips at single-organ level has made notable achievement during the last decade, multi-organ-on-a-chips, which manifests unique advantages, has started gathering attention only recently. In this viewpoint, we discuss the current status of organ-on-a-chip technology, with a specific emphasis on multi-organ-on-a-chip. Key technological advances contributing to the maturation of the field, and challenges that need to be addressed before wider adoption in relevant fields are discussed. We will share our perspectives on how the multi-organ-on-a-chip can improve the drug development process.

Keywords

Multi-organ-on-a-chip; Disease models; Drug development; In vitro model system

Cite This Article

SUNG, J. H. (2022). From organ-on-a-chip towards body-on-a-chip. BIOCELL, 46(5), 1177–1180.



This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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