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Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR): A critical overview on the most promising applications of molecular scissors in oral medicine

MARCO TATULLO1,*, LUISA LIMONGELLI2, ROSA MARIA MARANO3, ALESSANDRA VALLETTA4, ANGELA TEMPESTA2, SANDRO RENGO4

1 Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, Bari, 74124, Italy
2 Department of Interdisciplinary Medicine, University of Bari Aldo Moro, Bari, 74124, Italy
3 Marrelli Health-Tecnologica Research Institute, Biomedical Section, Stem Cells and Medical Genetics Units, Crotone, 88900, Italy
4 Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Naples, 80131, Italy

* Corresponding Author: Marco Tatullo, email

BIOCELL 2022, 46(8), 1837-1842. https://doi.org/10.32604/biocell.2022.020570

Abstract

The scientific community is continuously working to translate the novel biomedical techniques into effective medical treatments. CRISPR-Cas 9 system (Clustered Regularly Interspaced Short Palindromic Repeats-9), commonly known as the “molecular scissor”, represents a recently developed biotechnology able to improve the quality and the efficacy of traditional treatments, related to several human diseases, such as chronic diseases, neurodegenerative pathologies and, interestingly, oral diseases. Of course, dental medicine has notably increased the use of biotechnologies to ensure modern and conservative approaches: in this landscape, the use of CRISPR-Cas-9 system may speed and personalize the traditional therapies, ensuring a good predictability of clinical results. The aim of this critical overview is to provide evidence on CRISPR efficacy, taking into specific account its applications in oral medicine.

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APA Style
TATULLO, M., LIMONGELLI, L., MARANO, R.M., VALLETTA, A., TEMPESTA, A. et al. (2022). Clustered regularly interspaced short palindromic repeats (CRISPR): A critical overview on the most promising applications of molecular scissors in oral medicine. BIOCELL, 46(8), 1837-1842. https://doi.org/10.32604/biocell.2022.020570
Vancouver Style
TATULLO M, LIMONGELLI L, MARANO RM, VALLETTA A, TEMPESTA A, RENGO S. Clustered regularly interspaced short palindromic repeats (CRISPR): A critical overview on the most promising applications of molecular scissors in oral medicine. BIOCELL . 2022;46(8):1837-1842 https://doi.org/10.32604/biocell.2022.020570
IEEE Style
M. TATULLO, L. LIMONGELLI, R.M. MARANO, A. VALLETTA, A. TEMPESTA, and S. RENGO "Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR): A critical overview on the most promising applications of molecular scissors in oral medicine," BIOCELL , vol. 46, no. 8, pp. 1837-1842. 2022. https://doi.org/10.32604/biocell.2022.020570



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