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Treatment and Clinical Management of Chronic Thromboembolic Pulmonary Hypertension: An Update of Literature Review

Yuan Ren1, Yingxian Sun1, Zhiguang Yang2, Yanli Chen1,*
1 The Department of Cardiology, The First Affiliated Hospital of China Medical University, Shenyang, 110000, China
2 The Radiology Department, Shengjing Hospital of China Medical University, Shenyang, 110020, China
* Corresponding Author: Yanli Chen. Email: email

Congenital Heart Disease https://doi.org/10.32604/chd.2024.047930

Received 22 November 2023; Accepted 08 March 2024; Published online 08 April 2024

Abstract

Chronic thromboembolic pulmonary hypertension (CTEPH) is a chronic, progressive, debilitating, and life-threatening complication of pulmonary embolism (PE). Recent technological advances have permitted various treatment options for the treatment of CTEPH, including surgery, angioplasty, and medical treatment, depending on the location and characteristics of lesions. Pulmonary endarterectomy (PEA) is the treatment of choice for CTEPH, as it offers excellent long-term outcomes and a high probability of recovery. Moreover, various medical and interventional therapies are currently being developed for patients with inoperable CTEPH. This review mainly summarizes the current treatment approaches of CTEPH, offering more options for specialist physicians to, thus, better manage chronic thromboembolic syndromes.

Keywords

Chronic thromboembolic pulmonary hypertension (CTEPH); chronic thromboembolic pulmonary disease (CTEPD); pulmonary endarterectomy (PEA); balloon pulmonary angioplasty (BPA); COVID-19
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