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Hemodynamic Based Surgical Decision on Sequential Graft and Y-Type Graft in Coronary Artery Bypass Grafting

Xi Zhao, Youjun Liu∗,†, Wenxin Wang
College of Life Science and Bio-engineering, Beijing University of Technology, No. 100 Pingleyuan, Chaoyang District, Beijing, P. R. China. 100124.
E-mail: lyjlma@bjut.edu.cn

Molecular & Cellular Biomechanics 2015, 12(1), 49-66. https://doi.org/10.3970/mcb.2015.012.049

Abstract

Purpose: Sequential graft and Y-type graft are two different surgical procedures in coronary artery bypass grafting (CABG). The hemodynamic environment of them are different, that may cause different short-term surgical result and long-term patency. In this study, the short-term and long-term result of sequential and Y-type graft was discussed by comparing the hemodynamics of them. Materials and Methods: Two postoperative 3-dimensional (3D) models were built by applying different graft on a patient-specific 3D model with serious stenosis. Then zero-dimensional (0D)/3D coupled simulation was carried out by coupling the postoperative 3D models with a 0D lumped parameter model of the cardiovascular system. Results: The flow rate of native coronary arteries and grafts are all calculated and illustrated in this paper. No significant difference of the native coronary arteries flow and graft flow exists between two surgical procedures. The wall shear stress (WSS) and streamline were also depicted. The graft WSS of sequential graft is 19.1% higher than Y-type graft. While flow separation appears at the bifurcation of Y-type graft. Conclusion: The short-term outcomes of sequential graft and Y-type graft are almost the same. But it can be found from the hemodynamics factors that the longterm patency of the sequential graft is better.

Keywords

0D/3D coupling Simulation, Hemodynamics, Coronary Artery Bypass Grafting (CABG), Computational Fluid Dynamics (CFD)

Cite This Article

Zhao, X., Liu, Y., Wang, W. (2015). Hemodynamic Based Surgical Decision on Sequential Graft and Y-Type Graft in Coronary Artery Bypass Grafting. Molecular & Cellular Biomechanics, 12(1), 49–66.



This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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