Open Access

ARTICLE

Regorafenib-Induced Hand–Foot Skin Reaction Is More Severe on the Feet Than on the Hands

Yuma Nonomiya^*, Takashi Yokokawa^†, Kazuyoshi Kawakami^†, Kazuo Kobayashi^†, Takeshi Aoyama^†, Tomomi Takiguchi^†, Takahito Sugisaki^†, Kenichi Suzuki^†, Mitsukuni Suenaga^‡, Takeru Wakatsuki^‡, Kensei Yamaguchi^‡, Yoshikazu Sugimoto^*, Toshihiro Hama^†

* Division of Chemotherapy, Faculty of Pharmacy, Keio University, Minato-ku, Tokyo, Japan
† Department of Pharmacy, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan
‡ Department of Gastroenterological Chemotherapy, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan