Open Access

COMMENTARY

GlycoRNA: A new player in cellular communication

HYUNG SEOK KIM^*

Department of Biochemistry, Kosin University College of Medicine, Seo-gu, Busan, 49267, Republic of Korea

* Corresponding Author: HYUNG SEOK KIM. Email:

Oncology Research 2025, 33(5), 995-1000. https://doi.org/10.32604/or.2025.060616

Received 06 November 2024; Accepted 13 January 2025; Issue published 18 April 2025

Abstract

The discovery of glycosylated RNA molecules, known as glycoRNAs, introduces a novel dimension to cellular biology. This commentary explores the transformative findings surrounding glycoRNAs, emphasizing their unique roles in cancer progression and the therapeutic opportunities they present. GlycoRNAs, through interactions with lectins and immune receptors, may contribute to tumor immune evasion. Moreover, the therapeutic potential of this emerging knowledge includes interventions targeting glycoRNA synthesis and modulation of associated signaling pathways. By highlighting these critical insights, this commentary aims to encourage the development of innovative strategies that could improve cancer prognosis and treatment.

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