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  • Open Access

    ARTICLE

    Effects of Forefoot Shoe on Knee and Ankle Loading during Running in Male Recreational Runners

    Jingying Lu1, Datao Xu1, Wenjing Quan1,2, Julien S. Baker3, Yaodong Gu1,*

    Molecular & Cellular Biomechanics, Vol.19, No.2, pp. 61-75, 2022, DOI:10.32604/mcb.2022.019978 - 25 March 2022

    Abstract Objectives: Although overuse running injury risks for the ankle and knee are high, the effect of different shoe designs on Achilles tendon force (ATF) and Patellofemoral joint contact force (PTF) loading rates are unclear. Therefore, the primary objective of this study was to compare the ATF at the ankle and the PTF and Patellofemoral joint stress force (PP) at the knee using different running shoe designs (forefoot shoes vs. normal shoes). Methods: Fourteen healthy recreational male runners were recruited to run over a force plate under two shoe conditions (forefoot shoes vs. normal shoes). Sagittal plane ankle… More >

  • Open Access

    ARTICLE

    Injectable Collagen/CMC Soft Tissue Filler with Developed Flow Properties

    Reza Samanipour1, Aida Pourmostafa2, Adel Marzban2, Sara Tabatabaee3, Hasan Bahraminasab2, Amir Ali Hamidieh4, Amirhossein Tavakoli4,*

    Molecular & Cellular Biomechanics, Vol.19, No.2, pp. 97-104, 2022, DOI:10.32604/mcb.2022.019080 - 25 March 2022

    Abstract Based on the remarkable demand for facial reconstitute or reshape fillers due to the dermal defects arising from specific diseases, trauma, or aging, several natural or synthetic materials have been investigated. Among the evaluated materials, decellularized dermis is one of the most biocompatible choices for the aim of skin tissue regenerative approaches. On the other hand, Carboxymethyl Cellulose (CMC), a synthetic polysaccharide, with the desirable degradability, biomechanical stability, and nontoxicity seems to be an acceptable reinforcement agent for decellularized dermis. Thus, in this research, an injectable soft tissue filler contained of human-derived decellularized collagen and More >

  • Open Access

    ARTICLE

    A Study on the Effect of Core Strength Strengthening Training on Exercise-Induced Lumbar Injuries

    Xianghui Li*

    Molecular & Cellular Biomechanics, Vol.19, No.2, pp. 105-114, 2022, DOI:10.32604/mcb.2022.018736 - 25 March 2022

    Abstract Objective: This study aims to analyze the effect of core strength strengthening training on exercise-induced lumbar injuries. Methods: Sixteen athletes suffering from lumbar injuries were randomly divided into two groups, group A and group B. Group A performed core strength strengthening training, while group B only performed normal study and life. Before and after the experiment, the Visual Analogue Scale (VAS) score, lumbar spine mobility, Oswestry Disability Index (ODI) and overall effect evaluation of the two groups were recorded and compared. Results: After the experiment, the VAS score of group A decreased to 2.78 ± 1.89 points,… More >

  • Open Access

    ARTICLE

    Influence of Nutritional Supplementation and Sports Training on the Physical Fitness of Track and Field Athletes

    Wenbing Zhu*

    Molecular & Cellular Biomechanics, Vol.19, No.2, pp. 89-96, 2022, DOI:10.32604/mcb.2022.018522 - 25 March 2022

    Abstract This study aims to understand the influence of nutritional supplementation and sports training on the physical fitness of track and field athletes. Twenty track and field athletes from Chongqing Normal University were supplemented with nutrition and trained for eight weeks. Water, sugar, and vitamins were supplemented. They were trained three times a week, two hours each time. One hour was for special track and field training, and one hour was for physical training. Before and after the experiment, the body composition, sports quality, and functional movement screening (FMS) of the athletes were tested. Compared with More >

  • Open Access

    ARTICLE

    Numerical Analysis of Blood Flow through COVID-19 Infected Arteries

    Anupam Krishnan1, Anjana P. Anantharaman2,*

    Molecular & Cellular Biomechanics, Vol.19, No.2, pp. 77-88, 2022, DOI:10.32604/mcb.2022.018369 - 25 March 2022

    Abstract Computational Fluid Dynamics has become relevant in the study of hemodynamics, where clinical results are challenging to obtain. This paper discusses a 2-Dimensional transient blood flow analysis through an arterial bifurcation for patients infected with the Coronavirus. The geometry considered is an arterial bifurcation with main stem diameter 3 mm and two outlets. The left outlet (smaller) has a diameter of 1.5 mm and the right outlet (larger), 2 mm. The length of the main stem, left branch and right branch are fixed at 35 mm, 20 mm and 25 mm respectively. Viscosity change that… More >

  • Open Access

    ARTICLE

    Nuclear Stress-Strain State over Micropillars: A Mechanical In silico Study

    Rachele Allena1,*, Denis Aubry2

    Molecular & Cellular Biomechanics, Vol.19, No.1, pp. 1-16, 2022, DOI:10.32604/mcb.2022.018958 - 12 January 2022

    Abstract Cells adapt to their environment and stimuli of different origin. During confined migration through sub-cellular and sub-nuclear pores, they can undergo large strains and the nucleus, the most voluminous and the stiffest organelle, plays a critical role. Recently, patterned microfluidic devices have been employed to analyze the cell mechanical behavior and the nucleus self-deformations. In this paper, we present an in silico model to simulate the interactions between the cell and the underneath microstructured substrate under the effect of the sole gravity. The model lays on mechanical features only and it has the potential to assess… More >

  • Open Access

    ARTICLE

    Effect of Resistance Training and Spirulina platensis on Expression of IL-6, Gp130 Cytokines, JAK-STAT Signaling in Male Rats Skeletal Muscle

    Abdossaleh Zar1, Fatemeh Ahmadi1, Forouzan Karimi2,*, Mozhgan Ahmadi3, Roger Ramsbottom4

    Molecular & Cellular Biomechanics, Vol.19, No.1, pp. 51-59, 2022, DOI:10.32604/mcb.2022.018345 - 12 January 2022

    Abstract The effect of resistance training and a herbal supplement on muscular signaling pathways are limited. We investigated the expression of IL-6, Gp130, JAK and STAT after resistance training, and Spirulina platensis supplementation in animal muscle. Thirty-two male Sprague Dawley rats (weight: 290 ± 20 g, and 9 weeks of age) were divided into four groups: control (CO; n = 8), Spirulina platensis supplementation (SP; n = 8), resistance exercise (RE; n = 8), and Spirulina platensis + resistance exercise (SP + RE; n = 8). The resistance exercise group trained five sessions each week for eight weeks. Spirulina… More >

  • Open Access

    ARTICLE

    Lung Nodule Detection Based on YOLOv3 Deep Learning with Limited Datasets

    Zhaohui Bu1, Xuejun Zhang2,3,*, Jianxiang Lu4, Huan Lao5, Chan Liang2, Xianfu Xu2, Yini Wei2, Hongjie Zeng2

    Molecular & Cellular Biomechanics, Vol.19, No.1, pp. 17-28, 2022, DOI:10.32604/mcb.2022.018318 - 12 January 2022

    Abstract The early symptom of lung tumor is always appeared as nodule on CT scans, among which 30% to 40% are malignant according to statistics studies. Therefore, early detection and classification of lung nodules are crucial to the treatment of lung cancer. With the increasing prevalence of lung cancer, large amount of CT images waiting for diagnosis are huge burdens to doctors who may missed or false detect abnormalities due to fatigue. Methods: In this study, we propose a novel lung nodule detection method based on YOLOv3 deep learning algorithm with only one preprocessing step is… More >

  • Open Access

    ARTICLE

    Comparative Study on Biomechanics of Two Legs in the Action of Single-Leg Landing in Men’s Badminton

    Gang He*

    Molecular & Cellular Biomechanics, Vol.19, No.1, pp. 41-50, 2022, DOI:10.32604/mcb.2022.017044 - 12 January 2022

    Abstract This study aims to analyze the biomechanical difference between the two legs of male badminton players when they land on one leg, thereby providing some guidance for preventing sports injury. Ten male badminton players were selected as the subjects. They did the single-leg landing movement successfully three times. The kinematic data were obtained by the Vicon infrared high-speed motion capture system. The kinetic data were obtained by the KISTLER three-dimensional forcing measuring platform. The data were processed and analyzed. The center of gravity of the right leg on the X and Y axes were 0.25 ± 0.05… More >

  • Open Access

    ARTICLE

    Classification of Leukemia and Leukemoid Using VGG-16 Convolutional Neural Network Architecture

    G. Sriram1, T. R. Ganesh Babu2, R. Praveena2,*, J. V. Anand3

    Molecular & Cellular Biomechanics, Vol.19, No.1, pp. 29-40, 2022, DOI:10.32604/mcb.2022.016966 - 12 January 2022

    Abstract Leukemoid reaction like leukemia indicates noticeable increased count of WBCs (White Blood Cells) but the cause of it is due to severe inflammation or infections in other body regions. In automatic diagnosis in classifying leukemia and leukemoid reactions, ALL IDB2 (Acute Lymphoblastic Leukemia-Image Data Base) dataset has been used which comprises 110 training images of blast cells and healthy cells. This paper aimed at an automatic process to distinguish leukemia and leukemoid reactions from blood smear images using Machine Learning. Initially, automatic detection and counting of WBC is done to identify leukocytosis and then an… More >

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