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  • Open Access


    Certain Investigations on Melanoma Detection Using Non-Subsampled Bendlet Transform with Different Classifiers

    S. Poovizhi, T. R. Ganesh Babu, R. Praveena*

    Molecular & Cellular Biomechanics, Vol.18, No.4, pp. 201-219, 2021, DOI:10.32604/mcb.2021.017984

    Abstract Skin is the largest organ and outer enclosure of the integumentary system that protects the human body from pathogens. Among various cancers in the world, skin cancer is one of the most commonly diagnosed cancer which can be either melanoma or non-melanoma. Melanoma cancers are very fatal compared with non-melanoma cancers but the chances of survival rate are high when diagnosed and treated earlier. The main aim of this work is to analyze and investigate the performance of Non-Subsampled Bendlet Transform (NSBT) on various classifiers for detecting melanoma from dermoscopic images. NSBT is a multiscale and multidirectional transform based on… More >

  • Open Access


    A Review of the Role of ERp57 in Cancerous and Non-Cancerous Cell Physiology and its Potential as a Therapeutic Target

    Fatemeh Rahbar1, Avid Farhang Fagheh2, Ayda Khosravi2, Siavash Shariatzadeh2,3,*, Reza Akhavan-Sigari4

    Molecular & Cellular Biomechanics, Vol.18, No.4, pp. 187-199, 2021, DOI:10.32604/mcb.2021.017750

    Abstract The protein ERp57 is a stress-responsive protein, mainly exists in the endoplasmic reticulum (ER), and a small amount in the cell membrane, cytoplasm, nucleus and mitochondria, which is involved in the signal transduction from the cell surface, the regulation process that occurs in the nucleus, and the formation of polymer protein complexes involved in DNA repair. Various degrees of ERp57 dysregulation has been observed in many types of non-communicable diseases especially in cancers. Previous studies showed that the expression of ERp57 could play a key role in occurrence and development of cancers such as breast cancer, gastric cancer, ovarian cancer,… More >

  • Open Access


    Study on the Effect of Shoulder Training on the Mechanics of Tennis Serve Speed through Video Analysis

    Wei Jiang1,*, Gang He2

    Molecular & Cellular Biomechanics, Vol.18, No.4, pp. 221-229, 2021, DOI:10.32604/mcb.2021.017050

    Abstract Tennis service is an important part of winning a match. This study analyzed the mechanics of tennis serving speed and divided ten tennis players into two groups. One group carried out conventional training, while the other group carried out auxiliary training on shoulders through elastic band besides conventional training. The actions were photographed by cameras and analyzed. The results showed that the throwing height and hitting point height of the two groups improved after the experiment, and p < 0.05 in the comparison between Groups A and B; the ball deflection angle reduced after throwing, but the improvement of Group B was… More >

  • Open Access


    Numerical Simulation of Bone Plate with Fatigue Crack and Investigation of Attraction Hole for Retarding Crack Growth

    Zhonghang Zhao, Aimin Ji*, Changsheng Chen

    Molecular & Cellular Biomechanics, Vol.18, No.4, pp. 173-185, 2021, DOI:10.32604/mcb.2021.016238

    Abstract Premature fracture of the bone plate caused by fatigue crack is the main failure mode in treating femoral shaft fracture. In order to improve the durability of the plate, this study proposed a crack attraction hole (CAH) to retard the crack propagation based on the fracture mechanics. In this paper, a numerical model of the femoral fracture internal fixation system was constructed, in which the femur was developed using a validated simplified model. First, the fatigue crack initiation location was defined at the stress concentration through static analysis. Next, with the joint simulation method of Franc3D and ABAQUS, the fatigue… More >

  • Open Access


    The Influence of Drag on Nonlinear Oscillatory Flow through Concentric Annulus

    B. Umadevi1,*, C. V. Vinay1, P. A. Dinesh2

    Molecular & Cellular Biomechanics, Vol.18, No.4, pp. 157-172, 2021, DOI:10.32604/mcb.2021.015605

    Abstract A mathematical model has been developed to study the effect of particle drag parameter and frequency parameter on velocity and pressure gradient in nonlinear oscillatory two phase flow. The main purpose is to apply the model to study the combined effect of introduction of the catheter and elastic properties of the arterial wall on the pulsatile nature of the blood flow. We model the artery as an isotropic thin walled elastic tube and the catheter as a coaxial flexible tube. Blood is modeled as an incompressible particulate viscous Newtonian fluid. Perturbation technique has been applied to find the approximations for… More >

  • Open Access


    Impact of Coronary Artery Curvature on the Longitudinal Stent Foreshortening: Real-World Observations

    Yang Li1,#, Runxin Fang2,#, Renyun Wang1, Qiming Dai1, Zhiyong Li2,*, Genshan Ma1

    Molecular & Cellular Biomechanics, Vol.18, No.3, pp. 119-122, 2021, DOI:10.32604/mcb.2021.017503

    Abstract Longitudinal stent foreshortening is a known phenomenon, however, the impact of coronary artery curvature on longitudinal stent foreshortening remains unclear. The aim of this study is to determine the impact of coronary artery curvature on the longitudinal stent foreshortening in the real-world scenarios. A total of 86 consecutive patients underwent coronary stent implantation were included in the present study. The degree of coronary artery curvature was defined as the length of the coronary artery curvature divided by the straight length. Longitudinal stent foreshortening was defined as the stent length after implantation divided by the stent length before implantation. The mean… More >

  • Open Access


    Analysis of the Movement Track of Top Spinning Ball and Biomechanics in the Process of Hitting Tennis Ball

    Xia Xie*

    Molecular & Cellular Biomechanics, Vol.18, No.3, pp. 147-156, 2021, DOI:10.32604/mcb.2021.016246

    Abstract The aim of this study is to analyze the movement track of top spinning tennis ball and the biomechanics characteristics of tennis players. This study took ten tennis players as an example. The hitting process of the top spinning ball was captured by two PULNIX high-speed cameras. The images were processed by APAS motion analysis system. The results showed that the top spinning ball moved forward while rotating in the hitting process and showed a large attack force after rebounding from the land. In biomechanics, A and B had larger angles of upper limb joints and larger joint speed. The… More >

  • Open Access


    Comparison of Detection and Classification of Hard Exudates Using Artificial Neural System vs. SVM Radial Basis Function in Diabetic Retinopathy

    V. Sudha1,*, T. R. Ganesh Babu2, N. Vikram1, R. Raja2

    Molecular & Cellular Biomechanics, Vol.18, No.3, pp. 139-145, 2021, DOI:10.32604/mcb.2021.016056

    Abstract Diabetic Retinopathy (DR) is a disease that occurs in the eye which results in blindness as it passes to proliferative stage. Diabetes can significantly result in symptoms like blurring of vision, kidney failure, nervous damage. Hence it has become necessary to identify retinal damage that occurs in diabetic eye due to raised glucose level in its initial stage itself. Hence automated detection of anamoly has become very essential. The appearance of crimson and yellow lesions is considered as the earliest symptoms of DR which are called as hemorrhages and exudates. If DR is analysed at initial stage, blindness does not… More >

  • Open Access


    Surface Topography Assessments of Spine Shape Change within the Day in Healthy Male Adults

    Jianming Lu1,*, Liangliang Xiang2, Huw Wiltshire3

    Molecular & Cellular Biomechanics, Vol.18, No.3, pp. 123-129, 2021, DOI:10.32604/mcb.2021.015993

    Abstract Surface topography is a no-invasive, radiation-free method that can measure sufficient surface spine parameters by the structured back surface scan and a precise anatomical landmarks recognition. The purpose of the present study was to measure the spine shape parameter changes within the day via the DIERS Formetric 4D analysis system. Ten male healthy volunteers were recruited to participate in the experiment. All participants were sedentary people with the average sitting time during study or work t ≥ 8 h and without any back disease in the past six months. Data were analyzed by one-way ANOVA, which set time points within… More >

  • Open Access


    Study of Hepatocytes Polyploidization Peculiarities in Cholestatic Liver of Adult Rats

    Salome Kiparoidze1,*, Nino Karumidze2, Ekaterine Bakuradze1, Irina Modebadze1, Levan Rusishvili1, Dimitri Kordzaia2, Diana Dzidziguri1

    Molecular & Cellular Biomechanics, Vol.18, No.3, pp. 131-138, 2021, DOI:10.32604/mcb.2021.015596

    Abstract According to the literature, different mechanisms and kinetics proceeding of regenerative growth has been established using the basic models of liver regeneration (after resection or chemically induced). Hence, in order to determine general regularities of the adaptive-compensatory processes in various pathological conditions, the processes taking place in the cholestatic liver of adult white rats during the first four days after common bile duct ligation have been studied. It has been shown that in cholestatic liver, compensatory-adaptive processes take place with different kinetics compared to those after resection. In particular, in response to the increased functional load caused by destructive processes… More >

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