Zhihong Lv, Yong Xu, Xingkang Jiang^*

Canadian Journal of Urology, Vol.33, No.1, pp. 1-2, 2026, DOI:10.32604/cju.2026.079600 - 28 February 2026

Abstract This article has no abstract. More >

Kevin R. Loughlin

Canadian Journal of Urology, Vol.33, No.1, pp. 3-6, 2026, DOI:10.32604/cju.2026.079368 - 28 February 2026

Abstract This article has no abstract. More >

Qiang Li¹, Lan Wu², Yi Zhang¹, Di Huang³, Song Ou-Yang¹, Jia-Yu Yang³, Bing-Hui Li^3,*, Xian-Tao Zeng^1,3,4,5,*

Canadian Journal of Urology, Vol.33, No.1, pp. 7-20, 2026, DOI:10.32604/cju.2026.076741 - 28 February 2026

Abstract Objective: Current research highlights periodontal disease as a systemic inflammatory condition that may influence extra-oral diseases such as prostatic diseases, which prompted us to explore the potential association. To evaluate whether periodontal disease is associated with an increased risk of prostatic disease, including prostate cancer, benign prostatic hyperplasia (BPH), and prostatitis. Methods: A systematic search of observational studies concerning the relationship between periodontal disease and prostatic disease was performed in online databases PubMed, Embase, Web of Science, Scopus, CENTRAL, CNKI, and WanFang. Searches were conducted from database inception to 31 July 2025. Pooled hazard ratio… More >

Mingwei Zhan^1,#, Zhaokai Zhou^2,#, Jianpeng Zhang^3,#, Xin Wang⁴, Canxuan Li⁵, Bochen Pan⁶, Zhanyang Luo⁷, Wenjie Shi⁸, Yongjie Wang⁹, Minglun Li¹⁰, Weizhuo Wang^11,*, Run Shi^12,*, Jingyu Zhu^1,13,*

Canadian Journal of Urology, Vol.33, No.1, pp. 35-49, 2026, DOI:10.32604/cju.2026.076084 - 28 February 2026

Abstract Artificial intelligence (AI) is transforming the diagnostic landscape of malignant tumors in the urinary system, including prostate cancer, bladder cancer, and renal cell carcinoma (RCC). By integrating imaging, pathology, and molecular data, AI enhances the precision and reproducibility of tumor detection, grading, and risk stratification. In prostate cancer, AI-assisted multiparametric Magnetic resonance imaging (MRI) and digital pathology systems improve lesion localization and Gleason scoring. For bladder cancer, deep learning-based cystoscopy and radiomics models from Computed tomography/magnetic resonance imaging (CT/MRI) enable real-time lesion segmentation and non-invasive biomarker prediction, such as Programmed Cell Death-Ligand 1 (PD-L1) expression. More >

Bara Barakat^1,*, Bilal Al-Absi¹, Boris Hadaschik², Christian Rehme², Samer Schakaki³, Joerg Bauer¹

Canadian Journal of Urology, Vol.33, No.1, pp. 105-116, 2026, DOI:10.32604/cju.2026.071284 - 28 February 2026

Abstract Background: Artificial intelligence (AI)-assisted three-dimensional (3D) surgical platforms, integrated with augmented reality, have the potential to improve intraoperative anatomical recognition and provide surgeons with an immersive, dynamic operating environment during uro-oncological procedures. This review aims to examine the current applications of AI in robotic uro-oncology, with a particular focus on its role in facilitating intraoperative navigation during complex surgeries. Methods: A systematic literature search was performed across PubMed, the National Library of Medicine, MEDLINE, the Cochrane Central Register of Controlled Trials (CENTRAL), ClinicalTrials.gov, and Google Scholar to identify relevant studies published up to July 2025.… More >

Abdullah Esmeray, Huseyin Burak Yazili^*, Mucahit Gelmis, Nazim Furkan Gunay, Caglar Dizdaroglu, Faruk Ozgor, Yasar Pazir, Ufuk Caglar

Canadian Journal of Urology, Vol.33, No.1, pp. 165-171, 2026, DOI:10.32604/cju.2025.069657 - 28 February 2026

Abstract Objectives: Supracostal access during percutaneous nephrolithotomy (PCNL) increases the risk of pulmonary complications. Although routine postoperative thoracic imaging is commonly performed to detect these events, its clinical necessity remains controversial. This study aimed to assess the necessity of routine postoperative thoracic imaging for detecting pulmonary complications in patients undergoing supracostal mini percutaneous nephrolithotomy (m-PCNL) surgery. Methods: A retrospective analysis was conducted on data from patients who underwent supracostal m-PCNL between 2017 and 2022 in a tertiary center. Excluding patients under 18, with kidney/skeletal anomalies, or active thoracic disease, 112 eligible patients were included. Patients were… More >

Abdelkader Akkad, Franck Bruyere, Ali Bourgi^*

Canadian Journal of Urology, Vol.33, No.1, pp. 155-163, 2026, DOI:10.32604/cju.2025.069546 - 28 February 2026

Abstract Objectives: Uretero-enteric strictures are feared complications following cystectomy. Despite surgical advancements, particularly the rise of robot-assisted approaches, the risk factors associated with these strictures remain poorly defined. This study aimed to identify the risk factors associated with uretero-enteric anastomotic strictures after cystectomy, according to the surgical approach and type of urinary diversion (extracorporeal vs. intracorporeal). Methods: We conducted a single-center retrospective study including 340 patients who underwent cystectomy between 2016 and 2024 at Tours University Hospital. Clinical, biological, perioperative, and postoperative data were analyzed. The occurrence of a uretero-ileal anastomotic stricture was defined radiologically by… More >

Soukaina Azil^1,2,*, Yassmine Louanjli², Noureddine Louanjli², Moncef Benkhalifa³, Bouchra Ghazi^1,4,5

Canadian Journal of Urology, Vol.33, No.1, pp. 51-62, 2026, DOI:10.32604/cju.2025.069420 - 28 February 2026

Abstract Mammalian fertilization involves the migration of spermatozoa through the female reproductive system. Early embryonic development is a consequence of several steps and signaling pathways being activated, as well as biochemical and morphological modifications of spermatozoa that enable them to penetrate the membrane of mature oocytes.
There are some crucial steps known to clearly explain the process of fertilization, starting with hyperactivation of spermatozoa, mutual recognition, and binding of gametes mediated by receptors located on the surface membranes of both gametes. The final step is followed by oocyte activation, which is primarily triggered via sperm-derived factors, inducing a More >

Gilberto Chéchile Toniolo¹, Nuria Jornet^1,*, Jady Rojas¹, Natalia Tejedor¹, Santiago Carrara¹, Alicia Maccagno², Teresa Brufau¹

Canadian Journal of Urology, Vol.33, No.1, pp. 93-103, 2026, DOI:10.32604/cju.2026.069182 - 28 February 2026

Abstract Background: Low-dose rate (LDR) prostate brachytherapy is a recommended treatment of localized prostate cancer in current guidelines. The study aimed to determine biochemical relapse-free survival (BRFS) in patients treated with dynamic real-time low-dose rate (LDR) brachytherapy using Iodine 125 (I¹²⁵). Methods: We retrospectively reviewed 499 patients with localized prostate cancer treated with I¹²⁵ LDR real-time brachytherapy between 2003 and 2021. The mean patient age was 65 years (range: 45–84 years). Based on the National Comprehensive Cancer Network (NCCN) risk classification, 230 patients (46.1%) were categorized as low risk, 235 (47.1%) as intermediate risk, and 34 (6.8%)… More >

Yingxiu Chen¹, Zhongyu Ren¹, Jiasheng Yan², Yang Yu^1,*

Canadian Journal of Urology, Vol.33, No.1, pp. 143-154, 2026, DOI:10.32604/cju.2025.069041 - 28 February 2026

Abstract Objectives: Postmenopausal women with stress urinary incontinence (SUI) exhibit low androgen expression. This study aimed to evaluate the efficacy and safety of vaginal androgen combined with pelvic floor muscle training (PFMT) in the treatment of SUI in postmenopausal women. Methods: Postmenopausal women with SUI were recruited from Hainan West Central Hospital between January 2024 and March 2025. Participants were randomly assigned in a double-blind manner to receive either vaginal androgen cream combined with PFMT (treatment group) or a visually identical placebo cream (without androgens) combined with PFMT (control group). The vaginal cream was applied to… More >