F.C.C. Almeidaa
, P.M. da Silvab,c, M.N.C. Coelho Pinheiroa,d,*
Frontiers in Heat and Mass Transfer, Vol.12, pp. 1-9, 2019, DOI:10.5098/hmt.12.16
Abstract In the last decades, polymeric systems were essayed and applied successfully as vehicles for transdermal delivery devices of active principles.
Applications in contraception, pain control, and smoking cessation are already frequent. A crucial aspect in the development of new formulations is
the maintenance of the therapeutic drug concentration range for long periods. Recognizing this topic as interesting and challenging, simple models to
describe drug release from a transdermal device were developed with the purpose to perform a parametric sensitivity analysis. Assuming drug diffusion
within the polymeric delivery system as the dominant mechanism the models were developed and implemented. Transdermal patches… More >
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