Cemile Bagkur^1,*, Emrah Guler^2,3, Bilgen Kaymakamzade^4,5, Evren Hincal^4,5, Kaya Suer⁶

CMES-Computer Modeling in Engineering & Sciences, Vol.130, No.1, pp. 111-132, 2022, DOI:10.32604/cmes.2022.016957

Abstract While antibiotic resistance is becoming increasingly serious today, there is almost no doubt that more challenging times await us in the future. Resistant microorganisms have increased in the past decades leading to limited treatment options, along with higher morbidity and mortality. Klebsiella pneumoniae is one of the significant microorganisms causing major public health problems by acquiring resistance to antibiotics and acting as an opportunistic pathogen of healthcare-associated infections. The production of extended spectrum beta-lactamases (ESBL) is one of the resistance mechanisms of K. pneumoniae against antibiotics. In this study, the future clinical situation of ESBL-producing K. pneumoniae was investigated in… More >

Haifeng WANG^{1, 2, 3} , Hongxuan HE²

BIOCELL, Vol.42, No.2, pp. 47-54, 2018, DOI:10.32604/biocell.2018.07006

Abstract The emergence and spread of antibiotic resistance genes among Bacteria are a serious threat to global health. Their occurrence in animals which are in contact with humans is also important. The Chinese cobra (Naja atra, Elapidae), though a highly venomous species, is appreciated as food and as a source of materials used in traditional Chinese medicine. We are here reporting the isolation of multidrug-resistant Klebsiella pneumoniae (Enterobacteriaceae) from the lung of Naja atra, obtained from a snake farm in a Beijing suburb. Our study analyzed, using gene sequencing, the occurrence of antibiotic resistance genes (ARGs) in three K. pneumoniae… More >