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  • Open Access


    Near Future Perspective of ESBL-Producing Klebsiella pneumoniae Strains Using Mathematical Modeling

    Cemile Bagkur1,*, Emrah Guler2,3, Bilgen Kaymakamzade4,5, Evren Hincal4,5, Kaya Suer6

    CMES-Computer Modeling in Engineering & Sciences, Vol.130, No.1, pp. 111-132, 2022, DOI:10.32604/cmes.2022.016957

    Abstract While antibiotic resistance is becoming increasingly serious today, there is almost no doubt that more challenging times await us in the future. Resistant microorganisms have increased in the past decades leading to limited treatment options, along with higher morbidity and mortality. Klebsiella pneumoniae is one of the significant microorganisms causing major public health problems by acquiring resistance to antibiotics and acting as an opportunistic pathogen of healthcare-associated infections. The production of extended spectrum beta-lactamases (ESBL) is one of the resistance mechanisms of K. pneumoniae against antibiotics. In this study, the future clinical situation of ESBL-producing K. pneumoniae was investigated in… More >

  • Open Access


    Characterization of multidrug-resistant Klebsiella pneumoniae isolated from the Chinese cobra Naja atra in a Beijing suburb

    Haifeng WANG1, 2, 3 , Hongxuan HE2

    BIOCELL, Vol.42, No.2, pp. 47-54, 2018, DOI:10.32604/biocell.2018.07006

    Abstract The emergence and spread of antibiotic resistance genes among Bacteria are a serious threat to global health. Their occurrence in animals which are in contact with humans is also important. The Chinese cobra (Naja atra, Elapidae), though a highly venomous species, is appreciated as food and as a source of materials used in traditional Chinese medicine. We are here reporting the isolation of multidrug-resistant Klebsiella pneumoniae (Enterobacteriaceae) from the lung of Naja atra, obtained from a snake farm in a Beijing suburb. Our study analyzed, using gene sequencing, the occurrence of antibiotic resistance genes (ARGs) in three K. pneumoniaeMore >

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