Parul Verma¹, Sana Choudhary¹, Neha Naaz^1,*, Nidhi Sharma¹, Nora M. Al Aboud², Fatmah Ahmed Safhi³, Diaa Abd El Moneim^4,*

Phyton-International Journal of Experimental Botany, Vol.93, No.12, pp. 3347-3372, 2024, DOI:10.32604/phyton.2024.057592 - 31 December 2024

Abstract Cadmium (Cd) is a highly toxic heavy metal pollutant primarily introduced into the environment through anthropogenic activities. In plants, the absorption and retention of Cd lead to a cascade of morphological, physiological, and cytological alterations. Nigella sativa L., also known as black cumin, is an annual herb with important commercial and medicinal uses. Thymoquinone, the primary bioactive compound in Nigella sativa L., is renowned for its potential health benefits. The current experiment aimed to ascertain the effects of various concentrations (10, 20, 30, 40 and 50 ppm) of cadmium nitrate (Cd(NO₃₊)₂) on two Nigella sativa cultivars (AN20 and… More >

Pravej Alam^*, Thamer H. Al balawi

Phyton-International Journal of Experimental Botany, Vol.91, No.9, pp. 1923-1931, 2022, DOI:10.32604/phyton.2022.021334 - 13 May 2022

Abstract Bacterial leaf blight (BLB) caused by Xanthomonas oryzae pv. oryzae (Xoo) is one of the most damaging diseases to rice across the world. Various chemicals have been employed so far for the management of bacterial leaf blight. On the other hand, these compounds are damaging to the ecosystem and have an impact on non-target species such as humans and animals. As a result, there is a need to create a new natural inhibitor for BLB management. Deformylase (PDF) enzyme is present in all eubacteria and its necessity in bacterial protein synthesis reveals it as an attractive target… More >

NARAYANAN NAMPOOTHIRI V. P.¹, VIGNESH SUNDARARAJAN¹, PALLAVI DAN¹, G. DEVANAND VENKATASUBBU^2,*, SAHABUDEEN SHEIK MOHIDEEN^1,*

BIOCELL, Vol.45, No.5, pp. 1251-1262, 2021, DOI:10.32604/biocell.2021.015090 - 12 July 2021

Abstract Alzheimer’s disease (AD) is one of the most common forms of dementia. Cognitive dysfunction and memory loss are the two main clinical symptoms of AD. Drosophila melanogaster models of AD, which are based on overexpression of human amyloid β (Aβ) or human tau (hTau) protein, have been used to study the mechanism underlying AD and to screen potential therapeutic compounds. Drugs that are currently available for AD provide only symptomatic relief. Huge unmet medical needs exists to slow, stop, or reverse the progression of AD. Thymoquinone (TQ) is an active ingredient isolated from Nigella sativa (NS) and… More >