Flavia Oliveira Monteiro da Silva Abreu1,2,*, Taysse Holanda1, Joice Farias do Nascimento1, Henety Nascimento Pinheiro1, Rachel Menezes Castelo1, Hélcio Silva dos Santos3, Thais Benincá4, Patrícia da Silva Malheiros4, Júlio César Sousa Prado5, Raquel de Oliveira Fontenelle5, Maria Madalena de Camargo Forte2
Journal of Renewable Materials, Vol.12, No.2, pp. 285-304, 2024, DOI:10.32604/jrm.2023.043919
Abstract With the increase in antimicrobial resistance, it has become necessary to explore alternative approaches for combating and preventing diseases. DB-cinnamaldehyde (CNM) and Benzyl4-amino (B4AM) are bioactive compounds derived from chalcones but with restricted solubility in aqueous media. Nanoemulsions can enhance the solubility of compounds and can be a promising alternative in the development of novel antimicrobials, with reduced side effects and prolonged release. The objective of this study was to evaluate the stability of oil-in-water nanoemulsions loaded with two distinct types of chalcones at two different dosages, to propose a stable formulation with antimicrobial properties. Results showed that nanoemulsions presented… More >
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