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  • Open Access

    ARTICLE

    Hibifolin Modulates the Activation of Mouse Bone Marrow-Derived Dendritic Cells and Attenuates Contact Dermatitis Induced by 2,4-Dinitro-1-Fluorobenzene

    Ya-Yi Chen1,2, Tzu-Ting Chen3, Ya-Hsuan Chao4, Wen-Ho Chuo5, Chieh-Shan Wu6,7, Ruo-Han Tseng8,*, Chieh-Chen Huang9,*

    BIOCELL, Vol.49, No.9, pp. 1733-1748, 2025, DOI:10.32604/biocell.2025.067011 - 25 September 2025

    Abstract Objectives: Professional antigen-presenting cells known as dendritic cells (DCs) assist as a connection between the innate and adaptive components of the immune response. DCs are attractive targets for immunomodulatory drugs because of their crucial function in triggering immunity. This study set out to examine, for the first time, how hibifolin affected mouse bone-marrow derived (BMDCs) dendritic cells, triggered by lipopolysaccharide (LPS) in vitro. Additionally, a mouse model of contact hypersensitivity (CHS) was used to assess its possible therapeutic effects in vivo. Methods: LPS was administered to BMDCs with or without hibifolin. Major Histocompatibility Complex (MHC) class II,… More >

  • Open Access

    ARTICLE

    2,4-D Hyper Accumulation Induced Cellular Responses of Azolla pinnata R. Br. to Sustain Herbicidal Stress

    Arnab Kumar De, Arijit Ghosh, Debabrata Dolui, Indraneel Saha, Malay Kumar Adak*

    Phyton-International Journal of Experimental Botany, Vol.89, No.4, pp. 999-1017, 2020, DOI:10.32604/phyton.2020.010828 - 09 November 2020

    Abstract In the present experiment with ongoing concentration (0 µM, 100 µM, 250 µM, 500 µM and 1000 µM) of 2,4-D, the responses of Azolla pinnata R.Br. was evaluated based on cellular functions. Initially, plants were significantly tolerated up to 1000 µM of 2,4-D with its survival. This was accompanied by a steady decline of indole acetic acid (IAA) concentration in tissues with 78.8% over the control. Membrane bound H+ -ATPase activity was over expressed within a range of 1.14 to 1.25 folds with activator (KCl) and decreased within a range of 57.3 to 74.6% in response to… More >

  • Open Access

    ARTICLE

    Spores germination and gametophytes of Alsophila odonelliana (Cyatheaceae) in different sterile media

    Bonomo MC, OG Martínez, ME Tanco, R Cardozo, Z Avilés

    Phyton-International Journal of Experimental Botany, Vol.82, pp. 119-126, 2013, DOI:10.32604/phyton.2013.82.119

    Abstract The tree fern Alsophila odonelliana is found from southern Bolivia to northwestern Argentina, in the Tucuman-Bolivian forests. Spore germination was tested in three sterile nutritive media: Dyer (D), Murashige and Skoog (MS) and Knudson (K). We also evaluated the effect on gametophyte development of the addition of two growth regulators, BAP and 2,4-D to the culture medium Dyer; 2,4-D was evaluated using two concentrations: 0.1 and 2.0 mg/L, and BAP using three concentrations, 0.01; 0.1 and 1.0 mg/L. We found no significant differences in the germination of spores among all three media. We noted that supplementing More >

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