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    ARTICLE

    COVID-19 vaccine related hypermetabolic lymph nodes on PET/CT: Implications of inflammatory findings in cancer imaging

    FERDINANDO CALABRIA1, ANTONIO BAGNATO1, GIULIANA GUADAGNINO2, MARIA TOTEDA1, ANTONIO LANZILLOTTA1, STEFANIA CARDEI1, ROSANNA TAVOLARO1, MARIO LEPORACE1,*

    Oncology Research, Vol.31, No.2, pp. 117-124, 2023, DOI:10.32604/or.2023.027705

    Abstract We observed several patients presenting 2-[18F]FDG uptake in the reactive axillary lymph node at PET/CT imaging, ipsilateral to the site of the COVID-19 vaccine injection. Analog finding was documented at [18F]Choline PET/CT. The aim of our study was to describe this source of false positive cases. All patients examined by PET/CT were included in the study. Data concerning patient anamnesis, laterality, and time interval from recent COVID-19 vaccination were recorded. SUVmax was measured in all lymph nodes expressing tracer uptake after vaccination. Among 712 PET/CT scans with 2-[18F]FDG, 104 were submitted to vaccination; 89/104 patients (85%) presented axillary and/or deltoid… More >

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