LIPING GONG1, MING JIA2,*
BIOCELL, Vol.47, No.1, pp. 109-123, 2023, DOI:10.32604/biocell.2023.024620
Abstract ATP binding cassette subfamily C member 8 (ABCC8) encodes a protein regulating the ATP-sensitive
potassium channel. Whether the level of ABCC8 mRNA in lower grade glioma (LGG) correlates with immune cell
infiltration and patient outcomes has not been evaluated until now. Comparisons of ABCC8 expression between
different tumors and normal tissues were evaluated by exploring publicly available datasets. The association between
ABCC8 and tumor immune cell infiltration, diverse gene mutation characteristics, tumor mutation burden (TMB),
and survival in LGG was also investigated in several independent datasets. Pathway enrichment analysis was
conducted to search for ABCC8-associated signaling pathways. Through an online… More >
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