Olha Mykhailenko^1,2,3,#,*, Zigmantas Gudžinskas⁴, Liudas Ivanauskas⁵, Victoriya Georgiyants¹, Chia-Hung Yen^6,7,8, Chung-Fan Hsieh⁹, Riong Seulina Panjaitan⁶, Tsong-Long Hwang^10,11,12,13, Bing-Hung Chen^14,15, Michal Korinek^6,7,8,#,*

Phyton-International Journal of Experimental Botany, Vol.95, No.1, 2026, DOI:10.32604/phyton.2026.074209 - 30 January 2026

Abstract The sustainable sourcing of novel bioactive compounds from natural sources is crucial to the success of the pharmaceutical, food, and cosmetics industries. Iris bucharica Foster (syn. Juno bucharica (Foster) Vved.) is a promising source of novel bioactive molecules, particularly phenolic compounds, which are renowned for their antioxidant properties. In this study, we developed a reliable HPLC-UV-DAD method to identify and quantify phenolic compounds in the leaves and bulbs of I. bucharica, establishing the first set of quality control markers for this species. A total of 21 phenolic compounds were identified in the leaves, with flavonoids isoorientin, guaijaverin, hyperoside, More >

Mong-Fong Horng^1,#, Thanh-Lam Nguyen^1,#, Thanh-Tuan Nguyen^2,*, Chin-Shiuh Shieh^1,*, Lan-Yuen Guo³, Chen-Fu Hung⁴, Chun-Chih Lo¹

CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.1, 2026, DOI:10.32604/cmes.2025.075064 - 29 January 2026

Abstract The global population is rapidly expanding, driving an increasing demand for intelligent healthcare systems. Artificial intelligence (AI) applications in remote patient monitoring and diagnosis have achieved remarkable progress and are emerging as a major development trend. Among these applications, mouth motion tracking and mouth-state detection represent an important direction, providing valuable support for diagnosing neuromuscular disorders such as dysphagia, Bell’s palsy, and Parkinson’s disease. In this study, we focus on developing a real-time system capable of monitoring and detecting mouth state that can be efficiently deployed on edge devices. The proposed system integrates the Facial… More >

Haokai Xie¹, Yi Lu¹, Xiaojun Ni¹, Yilei Gu¹, Sihao Fu^2,*, Wenyao Ye³, Zheren Zhang², Zheng Xu²

Energy Engineering, Vol.123, No.2, 2026, DOI:10.32604/ee.2025.070934 - 27 January 2026

Abstract With the rapid development of large-scale offshore wind farms, efficient and reliable power transmission systems are urgently needed. Hybrid high-voltage direct current (HVDC) configurations combining a diode rectifier unit (DRU) and a modular multilevel converter (MMC) have emerged as a promising solution, offering advantages in cost-effectiveness and control capability. However, the uncontrollable nature of the DRU poses significant challenges for system stability under offshore AC fault conditions, particularly due to its inability to provide fault current or voltage support. This paper investigates the offshore AC fault characteristics and fault ride-through (FRT) strategy of a hybrid… More >

Zhitao Yang^1,#, Huanyu Cheng^1,#, Xinli Liu¹, Jie Li¹, Xin Ming¹, Beibei Li¹, Luyao Zhang¹, Chunqing MA¹, Yi Jiao¹, Shenjia Wu¹, Ibrar Muhammad Khan², Guanghua Xiong¹, Hongcheng Wang^1,*, Yong Liu^1,*

BIOCELL, Vol.50, No.1, 2026, DOI:10.32604/biocell.2025.072736 - 23 January 2026

Abstract Objectives: Postmenopausal osteoporosis is the most common form of osteoporosis in clinical practice, affecting millions of postmenopausal women worldwide. Postmenopausal osteoporosis demands safe and effective therapies. This study aimed to evaluate the potential of hederagenin (Hed) for treating osteoporosis and to elucidate its underlying mechanisms of action. Methods: The anti-osteoporotic potential of Hed was assessed by investigating its effects on ovariectomy (OVX)-induced bone loss in mice and on receptor activator of NF-kappaB ligand (RANKL)-induced osteoclast differentiation in RAW264.7 cells. Network pharmacology analysis and molecular docking were employed to identify key targets, which were subsequently validated experimentally. Results:… More >

Ahmed Awad Mohamed¹, Eslam Abdelhakim Seyam^2,*, Ahmed R. Elsaeed³, Laith Abualigah⁴, Aseel Smerat^5,6, Ahmed M. AbdelMouty⁷, Hosam E. Refaat⁸

CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.073171 - 12 January 2026

Abstract In recent years, fog computing has become an important environment for dealing with the Internet of Things. Fog computing was developed to handle large-scale big data by scheduling tasks via cloud computing. Task scheduling is crucial for efficiently handling IoT user requests, thereby improving system performance, cost, and energy consumption across nodes in cloud computing. With the large amount of data and user requests, achieving the optimal solution to the task scheduling problem is challenging, particularly in terms of cost and energy efficiency. In this paper, we develop novel strategies to save energy consumption across… More >

José Arturo Ramírez-Fernández¹, Henevith G. Méndez-Figueroa¹, Sebastián Ossandón^2,*, Ricardo Galván-Martínez³, Miguel Ángel Hernández-Pérez³, Ricardo Orozco-Cruz³

CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.072707 - 12 January 2026

Abstract In this study, artificial neural networks (ANNs) were implemented to determine design parameters for an impressed current cathodic protection (ICCP) prototype. An ASTM A36 steel plate was tested in 3.5% NaCl solution, seawater, and NS4 using electrochemical impedance spectroscopy (EIS) to monitor the evolution of the substrate surface, which affects the current required to reach the protection potential (Eprot). Experimental data were collected as training datasets and analyzed using statistical methods, including box plots and correlation matrices. Subsequently, ANNs were applied to predict the current demand at different exposure times, enabling the estimation of electrochemical More >

Manaliben Amin^*

Journal on Artificial Intelligence, Vol.8, pp. 1-18, 2026, DOI:10.32604/jai.2026.073895 - 07 January 2026

Abstract Artificial intelligence (AI) is steadily making its way into pharmaceutical validation, where it promises faster documentation, smarter testing strategies, and better handling of deviations. These gains are attractive, but in a regulated environment speed is never enough. Regulators want assurance that every system is reliable, that decisions are explainable, and that human accountability remains central. This paper sets out a Human-in-the-Loop (HITL) AI approach for Computer System Validation (CSV) and Computer Software Assurance (CSA). It relies on explainable AI (XAI) tools but keeps structured human review in place, so automation can be used without creating… More >

K. Naga Venkata Siva¹, Damodhar Reddy², P. Krishna Murthy³, Kiran Kumar Pulamolu⁴, M. Dharani⁵, T. Venkatakrishnamoorthy^6,*

Energy Engineering, Vol.123, No.1, 2026, DOI:10.32604/ee.2025.072982 - 27 December 2025

Abstract Conventional multilevel inverters often suffer from high harmonic distortion and increased design complexity due to the need for numerous power semiconductor components, particularly at elevated voltage levels. Addressing these shortcomings, this work presents a robust 15-level Packed U Cell (PUC) inverter topology designed for renewable energy and grid-connected applications. The proposed system integrates a sensor less proportional-resonant (PR) controller with an advanced carrier-based pulse width modulation scheme. This approach efficiently balances capacitor voltage, minimizes steady-state error, and strongly suppresses both zero and third-order harmonics resulting in reduced total harmonic distortion and enhanced voltage regulation. Additionally, More >

Binjiang Hu^1,*, Yihua Zhu², Liang Tu^1,2, Zun Ma³, Xian Meng³, Kewei Xu³

Energy Engineering, Vol.123, No.1, 2026, DOI:10.32604/ee.2025.069777 - 27 December 2025

Abstract This paper proposes an equivalent modeling method for photovoltaic (PV) power stations via a particle swarm optimization (PSO) K-means clustering (KMC) algorithm with passive filter parameter clustering to address the complexities, simulation time cost and convergence problems of detailed PV power station models. First, the amplitude–frequency curves of different filter parameters are analyzed. Based on the results, a grouping parameter set for characterizing the external filter characteristics is established. These parameters are further defined as clustering parameters. A single PV inverter model is then established as a prerequisite foundation. The proposed equivalent method combines the… More >

Junwen Huo, Haicheng Liang, Weiye Dong, Xiaoming Du^*

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-20, 2026, DOI:10.32604/cmc.2025.073285 - 09 December 2025

Abstract With the rapid advancement of electromagnetic launch technology, enhancing the structural stability and thermal resistance of armatures has become essential for improving the overall efficiency and reliability of railgun systems. Traditional aluminum alloy armatures often suffer from severe ablation, deformation, and uneven current distribution under high pulsed currents, which limit their performance and service life. To address these challenges, this study employs the Johnson–Cook constitutive model and the finite element method to develop armature models of aluminum matrix composites with varying heterogeneous graphene volume fractions. The temperature, stress, and strain of the armatures during operation… More >