JIECHUAN QIU1, TIANMIN YANG1, YANNING SUN2, KAI SUN2, YINGKUN XU3, QINGHUA XIA1,*
Oncology Research, Vol.32, No.3, pp. 545-561, 2024, DOI:10.32604/or.2023.030462
Abstract This research aims to identify the key fatty acid beta-oxidation (FAO) genes that are altered in kidney renal clear cell carcinoma (KIRC) and to analyze the role of these genes in KIRC. The Gene Expression Omnibus (GEO) and FAO datasets were used to identify these key genes. Wilcoxon rank sum test was used to assess the levels of acyl-CoA dehydrogenase medium chain (ACADM) between KIRC and non-cancer samples. The logistic regression and Wilcoxon rank sum test were used to explore the association between ACADM and clinical features. The diagnostic performance of ACADM for KIRC was assessed using a diagnostic receiver… More >
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