Jianye Li*, Bin Zhang†, Jizhao Cui‡, Zhen Liang§, Kexia Liu*
Oncology Research, Vol.27, No.7, pp. 789-799, 2019, DOI:10.3727/096504018X15444387696532
Abstract Many studies have shown that downregulated miR-203 level is in a variety of cancers including gastric cancer
(GC). However, the precise molecule mechanisms of miR-203 in GC have not been well clarified. In the current study, we investigated the biological functions and molecular mechanisms of miR-203 in GC cell lines.
We found that miR-203 is downregulated in GC tissues and cell lines. Moreover, the low level of miR-203
was associated with increased expression of annexin A4 in GC tissues and cell lines. The invasion and EMT
of GC cells were suppressed by overexpression of miR-203. However, downregulation of miR-203 promoted… More >
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