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  • Open Access

    ARTICLE

    Diagnostic Yield of Non-Invasive Testing in Patients with Anomalous Aortic Origin of Coronary Arteries: A Multicentric Experience

    Alberto Cipriani1,#, Pietro Bernardo Dall’Aglio1,#, Laura Mazzotta1, Domenico Sirico2, George Sarris3, Mark Hazekamp4, Thierry Carrel5, Alessandro Frigiola6, Vladimir Sojak4, Mauro Lo Rito6, Jurgen Horer7, Regine Roussin7, Julie Cleuziou8, Bart Meyns9, Jose Fragata10, Helena Telles10, Anastasios C. Polimenakos11, Katrien Francois12, Altin Veshti13, Jukka Salminen14, Alvaro Gonzalez Rocafort15, Matej Nosal16, Eleftherios Protopapas3, Roberto Tumbarello17, Patrizio Sarto18, Cinzia Pegoraro18, Raffaella Motta19, Giovanni Di Salvo2, Domenico Corrado1, Vladimiro L. Vida1, Massimo A. Padalino1,2,*

    Congenital Heart Disease, Vol.17, No.4, pp. 375-385, 2022, DOI:10.32604/chd.2022.019385

    Abstract Background: Anomalous aortic origin of a coronary artery (AAOCA) is a congenital heart disease with a 0.3%−0.5% prevalence. Diagnosis is challenging due to nonspecific clinical presentation. Risk stratification and treatment are currently based on expert consensus and single-center case series. Methods: Demographical and clinical data of AAOCA patients from 17 tertiary-care centers were analyzed. Diagnostic imaging studies (Bidimensional echocardiography, coronary computed tomography angiography [CCTA] were collected. Clinical correlations with anomalous coronary course and origin were evaluated. Results: Data from 239 patients (42% males, mean age 15 y) affected by AAOCA were collected; 154 had AAOCA involving the… More > Graphic Abstract

    Diagnostic Yield of Non-Invasive Testing in Patients with Anomalous Aortic Origin of Coronary Arteries: A Multicentric Experience

  • Open Access

    ARTICLE

    Family perception of unmet support needs following a diagnosis of congenital coronary anomaly in children: Results of a survey

    Hitesh Agrawal1,2, Oriana K. Wright3, Kathleen E. Carberry1,4, S. Kristen Sexson Tejtel1,2, Carlos M. Mery1,5, Silvana Molossi1,2

    Congenital Heart Disease, Vol.12, No.6, pp. 721-725, 2017, DOI: 10.1111/chd.12473

    Abstract Background: Long-term outcome data on patients with anomalous aortic origin of coronary arteries (AAOCA) is sparse and they are often managed in a nonuniform manner. There is subjective perception of anxiety and unmet needs in these patients and families.
    Methods: An online survey of 13 questions was sent to 74 families of patients with AAOCA between May and October 2015. Descriptive statistics were performed.
    Results: A total of 31 (47%) families responded. Of these, 27 expressed the need to interact with other patients/families with AAOCA. The majority were interested in either face-to-face meetings (77%) or online support groups… More >

  • Open Access

    ARTICLE

    Anatomic types of anomalous aortic origin of a coronary artery: A pictorial summary

    Hitesh Agrawal1,2, Carlos M. Mery1,3, Rajesh Krishnamurthy1, Silvana Molossi1,2

    Congenital Heart Disease, Vol.12, No.5, pp. 603-606, 2017, DOI:10.1111/chd.12518

    Abstract Anomalous aortic origin of a coronary artery is a congenital abnormality of the origin or course of a coronary artery that arises from the aorta. As commonly seen in congenital heart disease, a wide spectrum of anatomic variability is seen and hence, it is important for clinicians to document the precise anatomy and course of the anomalous vessel. This article describes coronary artery nomenclature using computerized tomography angiography and virtual angioscopy. These details are important for decision making, useful for surgical planning, and may have prognostic implications. More >

  • Open Access

    ARTICLE

    Current practices are variable in the evaluation and management of patients with anomalous aortic origin of a coronary artery: Results of a survey

    Hitesh Agrawal1,2, Carlos M. Mery1,3, Patrick E. Day4, S. Kristen Sexson Tejtel1,2, E. Dean McKenzie1,3,5, Charles D. Fraser Jr1,3, Athar M. Qureshi1,2, Silvana Molossi1,2

    Congenital Heart Disease, Vol.12, No.5, pp. 610-614, 2017, DOI:10.1111/chd.12511

    Abstract Background: Anomalous aortic origin of a coronary artery (AAOCA) is the second leading cause of sudden cardiac death in young athletes in the USA. Long-term outcome data for these patients are lacking to date. There is insufficient knowledge on the best approach to these patients and they are managed in a nonuniform manner.
    Methods: An online survey of 15 questions regarding management of AAOCA was sent out to 198 cardiac healthcare providers. The goal was to define gaps in knowledge to justify a dedicated scientific forum for discussion of AAOCA. Descriptive statistics were performed.
    Results: A total of… More >

  • Open Access

    ARTICLE

    Coronary artery anomalies: A multidisciplinary approach to shape the landscape of a challenging problem

    Silvana Molossi1,2, Hitesh Agrawal1,2

    Congenital Heart Disease, Vol.12, No.5, pp. 596-596, 2017, DOI:10.1111/chd.12490

    Abstract Coronary artery anomalies, particularly anomalous aortic origin of a coronary artery with an interarterial course, are associated with sudden cardiac arrest or death in the young. There is paucity of data on risk stratification and longitudinal follow up is lacking in these patients. Collaboration and sharing of data among specialized centers might shed much needed light in this complex problem. More >

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