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    REVIEW

    Anti-nutritional characteristics and mechanism of soybean agglutinin

    LI PAN1, JIAWEI LIU1, MOHAMMED HAMDY FAROUK2,*, GUIXIN QIN1,*, NAN BAO1, YUAN ZHAO1, HUI SUN1

    BIOCELL, Vol.45, No.3, pp. 451-459, 2021, DOI:10.32604/biocell.2021.014289

    Abstract Soybean agglutinin (SBA) is an important anti-nutritional factor in soybean. SBA can induce animal growth inhibition, cause pathological changes of intestinal tissue, and decrease in the immune system functioning. Recently, a great deal of research has been done on the effects of SBA on cell morphology, division, apoptosis, autophagy, as well as the correlated signal transduction pathway. This review mainly covers the chemical and biological characteristics of SBA, describes the multifaceted aspects of SBA anti-nutritional functions, and highlights the possible cellular and molecular mechanism of anti-nutritional effects of SBA. This review has important implications for the prevention and treatment of… More >

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