Ramesa Shafi BHAT1, Amina El GEZEERY2, Abir Ben BACHAN1, Mona Awad ALONAZI1, Leena Saleh ALSUHAIBANI1, Afaf El-ANSARY3,4
BIOCELL, Vol.43, No.2, pp. 65-71, 2019, DOI:10.32604/biocell.2019.07012
Abstract Fluoride is a key ingredient of many psychiatric drugs like fluoxetine (Prozac®, Fluoxetine®). Pregnant women
frequently use this drug as they suffer from depression and anxiety disorders during this period. Fluoxetine is able to
reach the fetus through the placenta and passes to the newborn through milk. In the present study, female Wistar rats
were treated with 5, 10, and 20 mg/L fluoxetine (containing 94% fluorides) from pregnancy day 10 to day 20. After
delivery, the levels of the enzymatic antioxidants in the brain of their offspring at postnatal day 2 were measured. The
results showed that, in all fluoxetine… More >
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