TARYN E. SYMON1, RAMÓN GAXIOLA-ROBLES1,2, CLAUDIA J. HERNÁNDEZ-CAMACHO3, TANIA ZENTENO-SAVÍN1,*
BIOCELL, Vol.45, No.6, pp. 1621-1630, 2021, DOI:10.32604/biocell.2021.016302
Abstract Marine mammals undergo cycles of tissue ischemia and reperfusion during the dive response. Reperfusion
injury can result in oxidative tissue damage and the activation of a pro-inflammatory immune response. The risk of
oxidative damage is reduced by antioxidants. Our hypothesis is that the reported higher antioxidant defenses within
marine mammal tissues provide additional protection in situations that produce oxidative stress, like inflammation, in
comparison to terrestrial mammal tissues. Leukocytes were isolated from the whole blood of Pacific bottlenose
dolphins (Tursiops truncatus gilli) and humans (Homo sapiens) and were exposed to lipopolysaccharides (LPS, 10 µg/mL)
in vitro to simulate a pro-inflammatory… More >
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