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    Fixed Electrical Charges and Mobile Ions Affect the Measurable Mechano-Electrochemical Properties of Charged-Hydrated Biological Tissues: The Articular Cartilage Paradigm

    Leo Q. Wan1,1, Chester Miller1,1, X. Edward Guo2,2, Van C. Mow1,1,3,3

    Molecular & Cellular Biomechanics, Vol.1, No.1, pp. 81-100, 2004, DOI:10.3970/mcb.2004.001.081

    Abstract The triphasic constitutive law [Lai, Hou and Mow (1991)] has been shown in some special 1D cases to successfully model the deformational and transport behaviors of charged-hydrated, porous-permeable, soft biological tissues, as typified by articular cartilage. Due to nonlinearities and other mathematical complexities of these equations, few problems for the deformation of such materials have ever been solved analytically. Using a perturbation procedure, we have linearized the triphasic equations with respect to a small imposed axial compressive strain, and obtained an equilibrium solution, as well as a short-time boundary layer solution for the mechano- electrochemical… More >

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