LIANHUAN MA1, SHOUPENG LIU2, XIAOWEN ZHEN1, WEIWEI QIAO1, LINA MA1, XIAOMIN ZHANG3,*
BIOCELL, Vol.46, No.8, pp. 1911-1916, 2022, DOI:10.32604/biocell.2022.019277
Abstract This study was designed to investigate the protective effects of Astaxanthin (AST) in rats with diabetes mellitus
(DM) induced by streptozotocin. SD rats were divided into control group (n = 5, only received normal saline), DM group
(n = 8) and AST + DM group (n = 8; AST: 50 mg/kg/day). DM rats were induced by intraperitoneal injection of
streptozocin (STZ, 65 mg/kg). Blood glucose level and body weight were determined at weeks 0, 2, 4, 6 and 8,
respectively. At week 8, kidney function was determined, together with expression of P53 and dynamin-related
protein-1 (Drp1) by Western blot analysis… More >
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