Xueying Huang*, Chun Yang†, Chun Yuan‡, Fei Liu‡, Gador Canton‡, Jie Zheng§, Pamela K. Woodard§, Gregorio A. Sicard¶, Dalin Tang||
Molecular & Cellular Biomechanics, Vol.6, No.2, pp. 121-134, 2009, DOI:10.3970/mcb.2009.006.121
Abstract Image-based computational models for atherosclerotic plaques have been developed to perform mechanical analysis to quantify critical flow and stress/strain conditions related to plaque rupture which often leads directly to heart attack or stroke. An important modeling issue is how to determine zero stress state from in vivo plaque geometries. This paper presents a method to quantify human carotid artery axial and inner circumferential shrinkages by using patient-specific ex vivo and in vivo MRI images. A shrink-stretch process based on patient-specific in vivo plaque morphology and shrinkage data was introduced to shrink the in vivo geometry first to find the zero-stress… More >
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