Sergio Andrés CARMINATI1,2, María Carolina BARBOSA2, Claudio Marcelo FADER1,2*
BIOCELL, Vol.42, No.1, pp. 13-16, 2018, DOI:10.32604/biocell.2018.07008
Abstract Autophagy is an essential cellular homeostatic mechanism by which intracellular components
are delivered into the lysosomes for degradation and recycling. Autophagy has been related with a
diversity of pathological or physiological dentary processes such as bone remodeling, skeletal aging,
osteoclastogenesis, osteoblastogenesis and different types of oral cancer. Platelet-rich plasma (PRP),
isolated from autologous blood, is a plasma preparation containing a higher concentration of platelets
which contains numerous different growth factors and cytokines that activate several cellular signaling
cascades. The purpose of this study is to investigate the effect of PRP on autophagy stimulation in
both osteoblast precursor 3T3-L1 and non-related… More >
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