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    ARTICLE

    Discrete Circular Distributions with Applications to Shared Orthologs of Paired Circular Genomes

    Tomoaki Imoto1, *, Grace S. Shieh2, *, Kunio Shimizu3

    CMES-Computer Modeling in Engineering & Sciences, Vol.123, No.3, pp. 1131-1149, 2020, DOI:10.32604/cmes.2020.08466

    Abstract For structural comparisons of paired prokaryotic genomes, an important topic in synthetic and evolutionary biology, the locations of shared orthologous genes (henceforth orthologs) are observed as binned data. This and other data, e.g., wind directions recorded at monitoring sites and intensive care unit arrival times on the 24-hour clock, are counted in binned circular arcs, thus modeling them by discrete circular distributions (DCDs) is required. We propose a novel method to construct a DCD from a base continuous circular distribution (CCD). The probability mass function is defined to take the normalized values of the probability density function at some pre-fixed… More >

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