Xinxiong FEI, Wenbin HU, Gangsheng WANG, Chunyan SU, Xuqun HUANG, Zhongjun JIANG*
BIOCELL, Vol.44, No.1, pp. 81-88, 2020, DOI:10.32604/biocell.2020.08125
Abstract Lung cancer poses a serious threat to human life with high incidence and miRNA is an important biomarker
in tumors. This study aimed to explore the effect of miR-143-3p on the biological function of lung cancer cells and the
underlying mechanism. Eighty-seven samples of lung cancer tissues and 81 samples of tumor-adjacent tissues from
patients undergoing radical lung cancer surgery in our hospital were collected. The lung cancer cells and lung fibroblast
cells (HFL-1) were purchased, and then miR-143-3p-mimics, miR-NC, si-CTNND1, and NC were transfected into
A549 and PC-9 cells to establish cell models. MiR-143-3p and CTNND1 expression levels were… More >
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