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    Remodeling of Strain Energy Function of Common Bile Duct post Obstruction

    Quang Dang1,1, Hans Gregersen2,2, Birgitte Duch2,2, Ghassan S. Kassab1,1

    Molecular & Cellular Biomechanics, Vol.2, No.2, pp. 53-62, 2005, DOI:10.3970/mcb.2005.002.053

    Abstract Biliary duct obstruction is an important clinical condition that affects millions of people worldwide. We have previously shown that the common bile duct (CBD) undergoes significant growth and remodelling post obstruction. The mechanical stress-strain relation is expected to change due to growth and remodeling in response to obstruction and hence pressure-overload. The objective of the present study was to characterize the material properties of the CBD of the sham group and at 3 hours, 12 hours, 2 days, 8 days and 32 days (n=5 in each group) after obstruction. The Fung's exponential strain energy function… More >

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