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    REVIEW

    The role of transcriptional factor brachyury in the development and repair of nucleus pulposus

    YINGHUI WU#, HONG ZHANG#, QIANG WANG, SUOYUAN LI, JUN SHEN*

    BIOCELL, Vol.46, No.6, pp. 1363-1364, 2022, DOI:10.32604/biocell.2022.018360

    Abstract Transcription factor Brachyury, a protein containing 435 amino acids, has been widely investigated and reported in notochord differentiation and nucleus pulposus development. The crucial functions and underlying mechanisms by Brachyury are discussed in this paper, which suggests Brachyury can be developed into a potential novel target for the therapy of intervertebral disc degeneration. More >

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