Ayoub Mhaouch^1,*, Wafa Gtifa², Turke Althobaiti³, Hamzah Faraj⁴, Mohsen Machhout¹

CMC-Computers, Materials & Continua, Vol.84, No.3, pp. 5637-5663, 2025, DOI:10.32604/cmc.2025.065525 - 30 July 2025

Abstract In medical imaging, accurate brain tumor classification in medical imaging requires real-time processing and efficient computation, making hardware acceleration essential. Field Programmable Gate Arrays (FPGAs) offer parallelism and reconfigurability, making them well-suited for such tasks. In this study, we propose a hardware-accelerated Convolutional Neural Network (CNN) for brain cancer classification, implemented on the PYNQ-Z2 FPGA. Our approach optimizes the first Conv2D layer using different numerical representations: 8-bit fixed-point (INT8), 16-bit fixed-point (FP16), and 32-bit fixed-point (FP32), while the remaining layers run on an ARM Cortex-A9 processor. Experimental results demonstrate that FPGA acceleration significantly outperforms the… More >

SOROUSH SOLEYMANI¹, MOHAMMAD DOROUDIAN^2,*, MAHDIEH SOEZI^3,4, ALI BELADI⁵, KIARASH ASGARI², ASO MOBARAKSHAHI², ARYANA AGHAEIPOUR², RONAN MACLOUGHLIN^6,7,8,*

Oncology Research, Vol.33, No.1, pp. 15-26, 2025, DOI:10.32604/or.2024.053069 - 20 December 2024

Abstract Brain metastasis and primary glioblastoma multiforme represent the most common and lethal malignant brain tumors. Its median survival time is typically less than a year after diagnosis. One of the major challenges in treating these cancers is the efficiency of the transport of drugs to the central nervous system. The blood-brain barrier is cooperating with advanced stages of malignancy. The blood-brain barrier poses a significant challenge to delivering systemic medications to brain tumors. Nanodrug delivery systems have emerged as promising tools for effectively crossing this barrier. Additionally, the development of smart nanoparticles brings new hope More >

Tawfeeq Shawly¹, Ahmed Alsheikhy^2,*

CMC-Computers, Materials & Continua, Vol.77, No.1, pp. 425-443, 2023, DOI:10.32604/cmc.2023.040561 - 31 October 2023

Abstract According to the World Health Organization (WHO), Brain Tumors (BrT) have a high rate of mortality across the world. The mortality rate, however, decreases with early diagnosis. Brain images, Computed Tomography (CT) scans, Magnetic Resonance Imaging scans (MRIs), segmentation, analysis, and evaluation make up the critical tools and steps used to diagnose brain cancer in its early stages. For physicians, diagnosis can be challenging and time-consuming, especially for those with little expertise. As technology advances, Artificial Intelligence (AI) has been used in various domains as a diagnostic tool and offers promising outcomes. Deep-learning techniques are… More >

Madona B. Sahaai^*, G. R. Jothilakshmi, E. Praveen, V. Hemath Kumar

Intelligent Automation & Soft Computing, Vol.36, No.2, pp. 1507-1521, 2023, DOI:10.32604/iasc.2023.032256 - 05 January 2023

Abstract Magnetic Resonance Imaging (MRI) is one of the important resources for identifying abnormalities in the human brain. This work proposes an effective Multi-Class Classification (MCC) system using Binary Robust Invariant Scalable Keypoints (BRISK) as texture descriptors for effective classification. At first, the potential Region Of Interests (ROIs) are detected using features from the accelerated segment test algorithm. Then, non-maxima suppression is employed in scale space based on the information in the ROIs. The discriminating power of BRISK is examined using three machine learning classifiers such as k-Nearest Neighbour (kNN), Support Vector Machine (SVM) and Random Forest More >

Husam Yahya¹, Dumitru Baleanu^2,3,4, Rabha W. Ibrahim^5,*, Nadia M.G. Al-Saidi⁶

CMC-Computers, Materials & Continua, Vol.74, No.2, pp. 2531-2539, 2023, DOI:10.32604/cmc.2023.033282 - 31 October 2022

Abstract The current study provides a quantum calculus-based medical image enhancement technique that dynamically chooses the spatial distribution of image pixel intensity values. The technique focuses on boosting the edges and texture of an image while leaving the smooth areas alone. The brain Magnetic Resonance Imaging (MRI) scans are used to visualize the tumors that have spread throughout the brain in order to gain a better understanding of the stage of brain cancer. Accurately detecting brain cancer is a complex challenge that the medical system faces when diagnosing the disease. To solve this issue, this research… More >

Mahmoud Ragab^1,2,3,*, Sultanah M. Alshammari⁴, Amer H. Asseri^2,5, Waleed K. Almutiry⁶

CMC-Computers, Materials & Continua, Vol.73, No.1, pp. 801-815, 2022, DOI:10.32604/cmc.2022.029140 - 18 May 2022

Abstract Brain cancer detection and classification is done utilizing distinct medical imaging modalities like computed tomography (CT), or magnetic resonance imaging (MRI). An automated brain cancer classification using computer aided diagnosis (CAD) models can be designed to assist radiologists. With the recent advancement in computer vision (CV) and deep learning (DL) models, it is possible to automatically detect the tumor from images using a computer-aided design. This study focuses on the design of automated Henry Gas Solubility Optimization with Fusion of Handcrafted and Deep Features (HGSO-FHDF) technique for brain cancer classification. The proposed HGSO-FHDF technique aims… More >

Elias Hossain¹, Md. Shazzad Hossain², Md. Selim Hossain³, Sabila Al Jannat⁴, Moontahina Huda⁵, Sameer Alsharif⁶, Osama S. Faragallah⁷, Mahmoud M. A. Eid⁸, Ahmed Nabih Zaki Rashed^9,*

CMC-Computers, Materials & Continua, Vol.72, No.3, pp. 4509-4523, 2022, DOI:10.32604/cmc.2022.025977 - 21 April 2022

Abstract Due to the difficulties of brain tumor segmentation, this paper proposes a strategy for extracting brain tumors from three-dimensional Magnetic Resonance Image (MRI) and Computed Tomography (CT) scans utilizing 3D U-Net Design and ResNet50, taken after by conventional classification strategies. In this inquire, the ResNet50 picked up accuracy with 98.96%, and the 3D U-Net scored 97.99% among the different methods of deep learning. It is to be mentioned that traditional Convolutional Neural Network (CNN) gives 97.90% accuracy on top of the 3D MRI. In expansion, the image fusion approach combines the multimodal images and makes a fused… More >

T. Jeslin^1,*, J. Arul Linsely²

CMC-Computers, Materials & Continua, Vol.71, No.1, pp. 171-182, 2022, DOI:10.32604/cmc.2022.020255 - 03 November 2021

Abstract Brain cancer is the premier reason for cancer deaths all over the world. The diagnosis of brain cancer at an initial stage is mediocre, as the radiologist is ineffectual. Different experiments have been conducted and demonstrated clearly that the algorithms for nodule segmentation are unsuccessful. Therefore, the research has consolidated incremental clustering focused on superpixel segmentation as an appropriate optimization approach for the accurate segmentation of pulmonary nodules. The key aim of the research is to refine brain CT images to accurately distinguish tumors and the segmentation of small-scale anomalous nodules in the brain region.… More >

R. Muthaiyan^1,*, Dr M. Malleswaran²

Computer Systems Science and Engineering, Vol.40, No.1, pp. 299-312, 2022, DOI:10.32604/csse.2022.018034 - 26 August 2021

Abstract In this paper, an Automated Brain Image Analysis (ABIA) system that classifies the Magnetic Resonance Imaging (MRI) of human brain is presented. The classification of MRI images into normal or low grade or high grade plays a vital role for the early diagnosis. The Non-Subsampled Shearlet Transform (NSST) that captures more visual information than conventional wavelet transforms is employed for feature extraction. As the feature space of NSST is very high, a statistical t-test is applied to select the dominant directional sub-bands at each level of NSST decomposition based on sub-band energies. A combination of… More >

MARGARET SIMONIAN^*

BIOCELL, Vol.45, No.6, pp. 1459-1463, 2021, DOI:10.32604/biocell.2021.017369 - 01 September 2021

Abstract Pediatric central nervous system tumors are the most common tumors in children, it constitute 15%–20% of all malignancies in children and are the leading cause of cancer related deaths in children. Proteogenomics is an emerging field of biological research that utilizes a combination of proteomics, genomics, and transcriptomics to aid in the discovery and identification of biomarkers for diagnosis and therapeutic purposes. Integrative proteogenomics analysis of pediatric tumors identified underlying biological processes and potential treatments as well as the functional effects of somatic mutations and copy number variation driving tumorigenesis. More >