LARISSA DANIELE BOBERMIN1,*, LARA SCOPEL MEDEIROS2, FERNANDA WEBER2, GIANCARLO TOMAZZONI DE OLIVEIRA2, LUCÉLIA SANTI3,4,5, WALTER ORLANDO BEYS-DA-SILVA3,4,5, CARLOS-ALBERTO GONÇALVES1,2,6, ANDRÉ QUINCOZES-SANTOS1,2,6
BIOCELL, Vol.46, No.12, pp. 2517-2523, 2022, DOI:10.32604/biocell.2022.021566
Abstract Glial cells are crucial for maintaining central nervous system (CNS) homeostasis. They actively participate in immune responses, as well as form functional barriers, such as blood-brain barrier (BBB), which restrict the entry of pathogens and inflammatory mediators into the CNS. In general, viral infections during the gestational period can alter the embryonic and fetal environment, and the related inflammatory response may affect neurodevelopment and lead to behavioral dysfunction during later stage of life, as highlighted by our group for Zika virus infection. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) induces a cytokine storm and, during pregnancy, may be related to a… More >
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