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    REVIEW

    Circulating tumor cells and circulating tumor DNA in breast cancer diagnosis and monitoring

    EFFAT ALEMZADEH1, LEILA ALLAHQOLI2, HAMIDEH DEHGHAN3, AFROOZ MAZIDIMORADI4, ALIREZA GHASEMPOUR3, HAMID SALEHINIYA5,*

    Oncology Research, Vol.31, No.5, pp. 667-675, 2023, DOI:10.32604/or.2023.028406

    Abstract Liquid biopsy, including both circulating tumor cells and circulating tumor DNA, is becoming more popular as a diagnostic tool in the clinical management of breast cancer. Elevated concentrations of these biomarkers during cancer treatment may be used as markers for cancer progression as well as to understand the mechanisms underlying metastasis and treatment resistance. Thus, these circulating markers serve as tools for cancer assessing and monitoring through a simple, non-invasive blood draw. However, despite several study results currently noting a potential clinical impact of ctDNA mutation tracking, the method is not used clinically in cancer diagnosis among patients and more… More > Graphic Abstract

    Circulating tumor cells and circulating tumor DNA in breast cancer diagnosis and monitoring

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