Randa M. Matter1, Iman A. Ragab1, Alaa M. Roushdy2, Ahmed G. Ahmed1, Hanan H. Aly1, Eman A. Ismail3
Congenital Heart Disease, Vol.13, No.1, pp. 118-123, 2018, DOI:10.1111/chd.12530
Abstract Objectives: Congenital heart defects are common noninfectious causes of mortality in children.
Bleeding and thrombosis are both limiting factors in the management of such patients. We
assessed the frequency of thrombocytopenia in pediatric patients with congenital cyanotic heart
disease (CCHD) and evaluated determinants of platelet count including immature platelet fraction
(IPF) and their role in the pathogenesis of thrombocytopenia.
Methods: Forty-six children and adolescents with CCHD during pre-catheter visits were studied;
median age was 20.5 months. Complete blood count including IPF as a marker of platelet production and reticulated hemoglobin content (RET-He) as a marker of red cell production and… More >
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