Alessandro Sgrò1, Thomas M. Drake2, Pedro Lopez‐Ayala3, Kevin Phan4
Congenital Heart Disease, Vol.14, No.6, pp. 1102-1112, 2019, DOI:10.1111/chd.12855
Abstract Background: Left cardiac sympathetic denervation (LCSD) has been proposed as
useful therapy for long QT syndrome (LQTS) and catecholaminergic polymorphic
ventricular tachycardia (CPVT), in addition to anti‐arrhythmic agents and implant‐
able cardioverter defibrillators. This study aimed to assess the current evidence for
LCSD and compare the open vs the video‐assisted thoracoscopic surgery (VATS)
approaches.
Methods: MEDLINE, Embase and Cochrane library databases were searched up to
December 2018 for studies reporting the long‐term outcomes of LCSD in LQTS,
CPVT patients. The incidence of cardiac events (CEs) before and after surgery, the
change in QTc interval, and surgical complications were pooled to… More >
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