Khaled Elenizi¹, Abdullah Sharaf Aldeen², Nasser Alotaibi^3,*, Nagy Fagir², Hussien Hado², Mubarak Aldossari²

Congenital Heart Disease, Vol.20, No.5, pp. 539-546, 2025, DOI:10.32604/chd.2025.071226 - 30 November 2025

Abstract Persistent left superior vena cava (PLSVC) is a rare congenital anomaly that may complicate cardiac procedures when associated with a dilated coronary sinus (CS) and conduction disturbances. We report the case of a 27-year-old male with Wilson’s disease who presented with complete heart block. Echocardiography showed biatrial enlargement and severe CS dilation, while contrast-enhanced computed tomography (CT) confirmed PLSVC draining into the CS without a bridging vein. Anatomical constraints prevented cardiac resynchronization therapy, and dual-chamber pacemaker implantation proved technically challenging due to lead placement difficulties. This case highlights the importance of thorough preoperative assessment and More >

Zhuoxi Feng^#,1, Jinyang Liu^#,2, Zihao Wu¹, Ziran Geng¹, Zhimin Liu^1,*

Congenital Heart Disease, Vol.20, No.5, pp. 625-636, 2025, DOI:10.32604/chd.2025.069214 - 30 November 2025

Abstract Congenitally corrected transposition of the great arteries (CCTGA) is a rare congenital heart disease characterized by atrioventricular, ventriculoarterial, and conduction system discordance, commonly accompanied by atrioventricular block (AVB). Pacing in patients with CCTGA and AVB (both pediatric and adult) poses challenges in strategy selection, procedural complexity, and clinical decision-making due to limited evidence. Conventional morphological left ventricular pacing is widely adopted but may induce ventricular dyssynchrony, heart failure, and tricuspid valve dysfunction. While cardiac resynchronization therapy serves as an upgrade for pacing-induced cardiomyopathy and heart failure, its application may be limited by coronary sinus anatomical… More >

Jadranka Separovic Hanzevacki¹, Marija Brestovac^1,*, Vlatka Reskovic Luksic¹, Blanka Glavas Konja¹, Martina Lovric Bencic¹, Josko Bulum¹, Darko Anic²

Congenital Heart Disease, Vol.16, No.5, pp. 469-475, 2021, DOI:10.32604/CHD.2021.015237 - 03 June 2021

Abstract Patients with complete transposition of the great arteries (TGA) treated by the Senning procedure have a higher risk of developing heart failure due to: a) additional work load of the systemic (morphologic right) ventricle (sRV), b) arrhythmias, mainly caused by surgical implications at the atria as well as c) worsening of systemic tricuspid regurgitation. We present a unique case of a female patient who developed all these complications, who was successfully treated and was able to carry out a twin pregnancy. This breakthrough approach was based on: 1. detecting reversibility potential of myocardial systolic dysfunction… More >

Shankar Baskar, Andrew N. Redington, Philip R. Khoury, Timothy K. Knilans, David S. Spar, Richard J. Czosek

Congenital Heart Disease, Vol.14, No.2, pp. 201-206, 2019, DOI:10.1111/chd.12684

Abstract Background: Traditional indices to evaluate biventricular (BiV) pacing are load dependent, fail to assess dynamic changes, and may not be appropriate in patients with congenital heart disease (CHD). We therefore measured the force‐frequency relationship (FFR) using tissue Doppler‐de‐ rived isovolumic acceleration (IVA) to assess the dynamic adaption of the myocardium and its vari‐ ability with different ventricular pacing strategies.
Methods: This was a prospective pilot study of pediatric and young adult CHD patients with biventricular or multisite pacing systems. Color‐coded myocardial velocities were recorded at the base of the systemic ventricular free wall. IVA was calculated at… More >