Ke Zhou1, Dongyu Li1, Xintong Zhang2, Wensheng Wang1, Shusen Li1, Guang Song2,*
Congenital Heart Disease, Vol.16, No.6, pp. 609-645, 2021, DOI:10.32604/CHD.2021.016396
Abstract Cardioplegia has been widely used to reduce myocardial injury during pediatric cardiac surgery; however, which
cardioplegia solution has the best protective effect has not been established. Thus, we compared the myocardial
protective effects of different cardioplegia solutions used in pediatric cardiac surgery. Seven databases were
searched to identify the relevant randomized controlled trials. A network meta-analysis with a Bayesian framework was conducted. The outcomes included the following biochemical and clinical outcomes: serum concentrations of the creatine kinase-myocardial band at 6 h postoperatively; cardiac troponin I (cTnI) at 4, 12, and 24 h
postoperatively; spontaneous beating after declamping; postoperative arrhythmias; inotropic… More >
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