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    ARTICLE

    Chronic stress effects on the apoptotic index of the adrenal cortex of pregnant rats

    ANDREA BOZZO*, CARLOS ALBERTO SOÑEZ*, MARÍA TERESA MUGNAINI*, ISABEL CECILIA PASTORINO*, ALICIA NÉLIDA ROLANDO*, MARÍA CRISTINA ROMANINI*, HÉCTOR FERNANDO GAUNA**

    BIOCELL, Vol.30, No.3, pp. 439-445, 2006, DOI:10.32604/biocell.2006.30.439

    Abstract Chronic stress by immobilization during gestation can alter several mechanisms that maintain homeostasis in adrenal gland. The aim of this work was to quantify the apoptotic index of adrenal cortex during mid-pregnancy and to prove cytological characteristics by electron microscopy. The apoptotic index did not present significant differences between the adrenal cortex areas of control and experimental rats in any of the three ages studied. The day of gestation influenced significantly on the apoptotic index in both groups. This index increased as gestation progressed. It may be concluded that chronic stress by immobilization might induce the increase of apoptotic index… More >

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