AMAYNA ZAKARIA, SYED ABDULLAH IBN ASADUZZAMAN, ZOBAYDA NAHAR, HAFSA JARIN SNIGDHA, TASKINA MURSHED, RASHED NOOR*
BIOCELL, Vol.45, No.3, pp. 483-487, 2021, DOI:10.32604/biocell.2021.014704
Abstract The extent and aggression of colorectal cancer is a worldwide public health threat. Extensive research has been
conducted on the pre-requisites leading to this fatal cancer. An array of genes along with their mutations and the signal
transduction pathways leading to the cellular transformation into the cancerous cells have been investigated. Based on the
knowledge gained so far, present review shortly discussed the role of the major genes especially those are involved in
instigating abnormalities in the cellular cycles, cellular proliferation and differentiation. A simple but novel molecular
scheme of the colorectal cancer development has also been plotted. More >
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