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    ABSTRACT

    Mechanical Characterization and Constitutive Modeling of Rabbit Aortas in Health and Diabetes

    Zhi Zhang1, Jianhua Tong1,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 43-43, 2019, DOI:10.32604/mcb.2019.05721

    Abstract Diabetes is a major risk factor to cause macrovascular diseases and plays a pivotal role in aortic wall remodeling. However, the effects of diabetes on elastic properties of aortas remain largely unknown. Thirty adult rabbits (1.6-2.2 kg) were collected and the type I diabetic rabbit model was induced by injection of alloxan. A total of 15 control and 15 diabetic rabbit (abdominal) aortas were harvested. Uniaxial and biaxial tensile tests were performed to measure ultimate tensile strength and to characterize biaxial mechanical behaviors of the aortas. A material model was fitted to the biaxial experimental data to obtain constitutive parameters.… More >

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