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    Simulation of a Single Red Blood Cell Flowing Through a Microvessel Stenosis Using Dissipative Particle Dynamics

    L. L. Xiao, S. Chen∗,†, C. S. Lin, Y. Liu

    Molecular & Cellular Biomechanics, Vol.11, No.1, pp. 67-85, 2014, DOI:10.3970/mcb.2014.011.067

    Abstract The motion and deformation of a single red blood cell flowing through a microvessel stenosis was investigated employing dissipative particle dynamics (DPD) method. The numerical model considers plasma, cytoplasm, the RBC membrane and the microvessel walls, in which a three dimensional coarse-grained spring network model of RBC’s membrane was used to simulate the deformation of the RBC. The suspending plasma was modelled as an incompressible Newtonian fluid and the vessel walls were regarded as rigid body. The body force exerted on the free DPD particles was used to drive the flow. A modified bounce-back boundary condition was enforced on the… More >

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