XUELIAN CHEN^1,*, YUNZHENG ZHANG², JUNJIAN HE³, YIBING LI⁴

BIOCELL, Vol.47, No.10, pp. 2283-2300, 2023, DOI:10.32604/biocell.2023.030086

Abstract Background: The late detection of endometrial carcinoma (EC) at an advanced stage often results in a poor patient prognosis. It is hence important to identify reliable biomarkers to facilitate early detection of EC. Signal transducer and activator of transcription (STAT) family members play an important role in several tumors, however, their impact on EC development and progression remains unclear. Methods: Machine learning methods were used to investigate the importance of STAT5B in EC. Results: Hence, we explored the UALCAN data mining platform and found that while STAT1 and STAT2 were upregulated, STAT5A, STAT5B, and STAT6 were downregulated in EC. This… More >

Tawfeeq Shawly¹, Ahmed Alsheikhy^2,*

CMC-Computers, Materials & Continua, Vol.77, No.1, pp. 425-443, 2023, DOI:10.32604/cmc.2023.040561

Abstract According to the World Health Organization (WHO), Brain Tumors (BrT) have a high rate of mortality across the world. The mortality rate, however, decreases with early diagnosis. Brain images, Computed Tomography (CT) scans, Magnetic Resonance Imaging scans (MRIs), segmentation, analysis, and evaluation make up the critical tools and steps used to diagnose brain cancer in its early stages. For physicians, diagnosis can be challenging and time-consuming, especially for those with little expertise. As technology advances, Artificial Intelligence (AI) has been used in various domains as a diagnostic tool and offers promising outcomes. Deep-learning techniques are especially useful and have achieved… More >

A. Manju¹, R. kaladevi², Shanmugasundaram Hariharan³, Shih-Yu Chen^4,5,*, Vinay Kukreja⁶, Pradip Kumar Sharma⁷, Fayez Alqahtani⁸, Amr Tolba⁹, Jin Wang¹⁰

CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 993-1007, 2023, DOI:10.32604/cmc.2023.039567

Abstract The medical community has more concern on lung cancer analysis. Medical experts’ physical segmentation of lung cancers is time-consuming and needs to be automated. The research study’s objective is to diagnose lung tumors at an early stage to extend the life of humans using deep learning techniques. Computer-Aided Diagnostic (CAD) system aids in the diagnosis and shortens the time necessary to detect the tumor detected. The application of Deep Neural Networks (DNN) has also been exhibited as an excellent and effective method in classification and segmentation tasks. This research aims to separate lung cancers from images of Magnetic Resonance Imaging… More >

Mujeeb Ur Rehman^1,*, Maha Driss^2,3, Abdukodir Khakimov⁴, Sohail Khalid¹

CMC-Computers, Materials & Continua, Vol.72, No.3, pp. 5681-5697, 2022, DOI:10.32604/cmc.2022.025840

Abstract Lungs are a vital human body organ, and different Obstructive Lung Diseases (OLD) such as asthma, bronchitis, or lung cancer are caused by shortcomings within the lungs. Therefore, early diagnosis of OLD is crucial for such patients suffering from OLD since, after early diagnosis, breathing exercises and medical precautions can effectively improve their health state. A secure non-invasive early diagnosis of OLD is a primordial need, and in this context, digital image processing supported by Artificial Intelligence (AI) techniques is reliable and widely used in the medical field, especially for improving early disease diagnosis. Hence, this article presents an AI-based… More >

Atif Mehmood^1,*, Ahed Abugabah¹, Ahmed Ali AlZubi², Louis Sanzogni³

Computer Systems Science and Engineering, Vol.43, No.1, pp. 305-315, 2022, DOI:10.32604/csse.2022.018520

Abstract Alzheimer’s disease (AD) is a neurodegenerative disorder, causing the most common dementia in the elderly peoples. The AD patients are rapidly increasing in each year and AD is sixth leading cause of death in USA. Magnetic resonance imaging (MRI) is the leading modality used for the diagnosis of AD. Deep learning based approaches have produced impressive results in this domain. The early diagnosis of AD depends on the efficient use of classification approach. To address this issue, this study proposes a system using two convolutional neural networks (CNN) based approaches for an early diagnosis of AD automatically. In the proposed… More >

Omar M. El-Habbak¹, Abdelrahman M. Abdelalim¹, Nour H. Mohamed¹, Habiba M. Abd-Elaty¹, Mostafa A. Hammouda¹, Yasmeen Y. Mohamed¹, Mohanad A. Taifor¹, Ali W. Mohamed^2,3,*

CMC-Computers, Materials & Continua, Vol.70, No.2, pp. 2953-2969, 2022, DOI:10.32604/cmc.2022.020109

Abstract Parkinson’s disease (PD), one of whose symptoms is dysphonia, is a prevalent neurodegenerative disease. The use of outdated diagnosis techniques, which yield inaccurate and unreliable results, continues to represent an obstacle in early-stage detection and diagnosis for clinical professionals in the medical field. To solve this issue, the study proposes using machine learning and deep learning models to analyze processed speech signals of patients’ voice recordings. Datasets of these processed speech signals were obtained and experimented on by random forest and logistic regression classifiers. Results were highly successful, with 90% accuracy produced by the random forest classifier and 81.5% by… More >