Muzi Li^1,4, Hong Meng^1,4,*, Liang Zhang², Yuzi Zhou³, Chao Liang⁴, Zhiling Luo⁴, Hao Wang^1,*

Congenital Heart Disease, Vol.17, No.3, pp. 231-244, 2022, DOI:10.32604/chd.2022.019480

Abstract Background: Children are at risk of extubation failure after congenital heart disease surgery. Such cases should be identified to avoid possible adverse consequences of failed extubation. This study aimed to identify ultrasound predictors of successful extubation in children who underwent cardiac surgery. Methods: Children aged 3 months to 6 years who underwent cardiac surgery (if they were intubated for >6 h and underwent a spontaneous breathing trial) were included in this study. Results: We included 83 children who underwent surgery for congenital heart disease. Transthoracic echocardiography and lung ultrasound were performed immediately before spontaneous breathing trials. Upon spontaneous breathing trial… More >

Ling Sun^1,#, Chengcheng Pang^1,#, Xiaoyan Wang^2,#, Mingguo Xu³, Zhiwei Zhang^1,*, Shushui Wang^1,*

Congenital Heart Disease, Vol.17, No.2, pp. 201-214, 2022, DOI:10.32604/chd.2022.018453

Abstract Background: Partial anomalous pulmonary venous connection (PAPVC) is frequently associated with atrial septal defect (ASD), especially sinus venosus defect (SVD). Although Waggstaffe described the pathology of SVDs in 1868, the exact anatomic features and the nature of SVD remains controversial. SVDs with no posterior atrial rim were observed in recent years. However, no studies suggested that absence of the residual posterior atrial septal tissue might be the key feature of SVD. The aims of this study were to investigate if absence of posterior rim of atrial septum played a crucial role in patients with SVD. Methods: From January 2011 to… More >

Allard T. van den Hoven¹, Sultan Yilmazer¹, Lidia R. Bons¹, Roderick W. J. van Grootel¹, L. W. Geenen¹, An M. van Berendoncks¹, Anthonie L. Duijnhouwer², Hans-Marc J. Siebelink³, Jolien W. Roos-Hesselink¹, Annemien E. van den Bosch^1,*

Congenital Heart Disease, Vol.16, No.4, pp. 357-368, 2021, DOI:10.32604/CHD.2021.014462

Abstract Aim: This study aimed to describe the systolic left ventricular global longitudinal strain (LvGLS) and left ventricular peak early diastolic strain rate (Sre) in adult women with Turner syndrome (TS) and to determine its relationship with exercise capacity and clinical parameters. Methods: In this cross-sectional cohort study, consecutively included adult TS women underwent an electrocardiogram, transthoracic echocardiogram (TTE) and cardiopulmonary exercise test (CPET) on the same day. LvGLS and Sre were measured using 2D speckle tracking analysis (STE) and compared with age-matched healthy female controls. Results: Ninety-four adult women (age 36 ± 13 years) with TS and 32 healthy age-matched… More >

Roderick W. J. van Grootel, Allard T. van den Hoven, Dan Bowen, Tijmen Ris, Jolien W. Roos-Hesselink, Annemien E. van den Bosch^*

Congenital Heart Disease, Vol.16, No.3, pp. 221-232, 2021, DOI:10.32604/CHD.2021.013793

Abstract Aims: To assess the prognostic value of left ventricular (LV) global longitudinal strain (GLS) and global longitudinal early diastolic strain rate (GLSre) with regard to cardiovascular events, as congenital aortic stenosis (AoS) is associated with significant mortality and morbidity but predictors for clinical outcome are scarce. Strain analysis provides a robust and reproducible method for early detection of LV dysfunction, which might be of prognostic value. Methods: This prospective study, included clinically stable patients with congenital AoS between 2011–2013. LV GLS and GLSre was performed in the apical 4, 3 and 2-chamber views using Tomtec software. The endpoint was a… More >

Nunzia Borrelli^1,2, Jolanda Sabatino^1,3, Martina Avesani^1,4, Josefa Paredes¹, Manjit Josen¹, Alain Fraisse¹, Paolo Guccione², Guido Michielon¹, Giovanni Di Salvo^1,4,*

Congenital Heart Disease, Vol.16, No.1, pp. 27-37, 2021, DOI:10.32604/CHD.2021.012526

Abstract Background: Still little is known about the impact on right ventricle function of the 2 main approaches to Norwood palliation in Hypoplastic left heart syndrome, the right ventricle-pulmonary artery shunt (RVPAS) and the modified Blalock-Taussig shunt (mBTS). Methods: The cohort included 27 patients with Hypoplastic left heart syndrome (10 in the mBTS group, 17 in the RVPAS group). Longitudinal strain, tricuspid annulus peak systolic excursion and fractional area change were evaluated before Norwood and in four different breakpoints in the steady-state after Norwood procedure (30-days, 90-days, 140-days and 200-days after Norwood). Results: No significant differences were found in all standard… More >

Naveed Rabbani^1,*, Sarah Hofman DeYoung², Ronald L. Gibson², Jeffrey Conwell¹, Jason F. Deen¹

Congenital Heart Disease, Vol.15, No.4, pp. 197-201, 2020, DOI:10.32604/CHD.2020.011527

Abstract Persistent left superior vena cava (PLSVC) is a relatively common congenital venous anomaly that typically drains into the coronary sinus without hemodynamic significance. Rarely a PLSVC drains directly into the left atrium, forming a right-to-left shunt that can result in hypoxemia and potential paradoxical embolism. We present the case of a 2-year-old medically complex child on chronic mechanical ventilation with eventual diagnosis of episodic hypoxemia due to a PLSVC draining into the left atrium with position-dependent venous flow. The lesion was identified with contrast echocardiography and cardiac MRI. Subsequent occlusion with a vascular plug resulted in resolution of the child’s… More >

Mohd Nizam Mat Bah^*, Mohd Hanafi Sapian, Hasliza Razak, Emieliyuza Yusnita Alias

Congenital Heart Disease, Vol.15, No.4, pp. 203-216, 2020, DOI:10.32604/CHD.2020.013057

Abstract Introduction: Fetal echocardiogram allows early detection of critical congenital heart disease leading to a better outcome. However, data from lowerand middle-income countries is scarce. This study aims to evaluate the diagnostic error of fetal echocardiography and its impact on planned neonatal management. Methods and material: This retrospective observational cohort study includes all high-risk pregnant mothers who had fetal echocardiograms from 2008 to 2017. Fetal and postnatal echocardiograms were compared, while the diagnostic errors were categorized into false positive, false negative, and discrepant diagnoses. The impact of the diagnostic error on planned neonatal management and the long-term outcome was determined by… More >

Karina V. Bunting^1,2,*, Francesco Formisano³, Jennifer Green¹, Richard P. Steeds^1,2, Lucy Hudsmith¹, Paul Clift^1,2

Congenital Heart Disease, Vol.15, No.2, pp. 89-100, 2020, DOI:10.32604/CHD.2020.011376

Abstract Objective: To determine the accuracy of assessing univentricular function in adult Fontan patients using three-dimensional (3D) volumetric echocardiography. Design: A prospective observational study in an adult Fontan patient cohort. Setting: University Hospitals Birmingham, NHS Foundation Trust. Patients: 26 patients were enrolled in the study all aged over 18 years, possessing the Fontan anatomy, with no contraindications to Cardiac Magnetic Resonance (CMR) imaging and in sinus rhythm. Intervention: All patients underwent transthoracic echocardiography using a Philips EPIQ 7 and X5-1 transducer. End diastolic volume (EDV), end systolic volume (ESV), stroke volume (SV) and ejection fraction (EF) were obtained using two dimensional… More >

Ylenia Bartolacelli^*, Giulia Bragantini

Congenital Heart Disease, Vol.15, No.2, pp. 59-68, 2020, DOI:10.32604/CHD.2020.011448

Abstract Objective: The objective of this study was to assess left ventricle (LV) function and remodeling by three-dimensional echocardiography (3DE) in patients who underwent arterial switch procedure (ASO) for transposition of great arteries (TGA) in long-term follow-up. Methods and Results: We studied 54 asymptomatic patients (39 male) who have undergone single-stage ASO for TGA, aged 13.7 ± 4.7 years, with a normal LV ejection fraction (EF), compared to healthy peers. We evaluated LV volume and function in asymptomatic patients with normal ejection fraction by 3DE. All patients had normal EF, measured by modified Simpson’s method (mean 60.9 ± 3.5%) and by… More >

An Van Berendoncks^1,2, Roderick Van Grootel¹, Jackie McGhie¹, Matthijs van Kranenburg¹, Myrthe Menting¹, Judith A.A.E. Cuypers¹, Ad J.J.C. Bogers³, Maarten Witsenburg¹, Jolien W. Roos‐Hesselink¹, Annemien E. van den Bosch¹

Congenital Heart Disease, Vol.14, No.4, pp. 628-637, 2019, DOI:10.1111/chd.12762

Abstract Aims: Reliable evaluation of the severity and consequences of pulmonary regurgita‐ tion (PR) in patients with repaired tetralogy of Fallot (TOF) is crucial to timely identify the need for pulmonary valve intervention. We aimed to identify the accuracy of echocardiographic parameters to differentiate between moderate and severe PR, using phase contrast cardiac magnetic resonance imaging (CMR) as gold standard.
Methods and results: In this cross‐sectional study, 45 TOF patients with both echo‐ cardiographic and CMR measurements of PR were enrolled. All quantitative and semiquantitative echocardiographic measurements such as pressure half time (PHT), Color flow jet width (CFJW), ratio CFJW/right ventricle… More >