Alireza Mohammadkarim1, Manijhe Mokhtari-Dizaji2,*, Ali Kazemian3, Hazhir Saberi4, Mohammad Mehdi Khani5, Mohsen Bakhshandeh6
Molecular & Cellular Biomechanics, Vol.16, No.4, pp. 275-287, 2019, DOI:10.32604/mcb.2019.06280
Abstract The mechanical properties of living cells are known to be promising biomarkers when investigating the health and functions of the human body. Ionizing irradiation results in vascular injury due to endothelial damage. Thus, the current study objective was to evaluate the influence of continuous radiation doses on the mechanical properties of human umbilical vein endothelial cells (HUVECs), and to identify Young’s modulus (E) and viscoelastic behavior. Single-dose (0, 2, 4, 6, and 8 Gy) radiation was applied to HUVECs using a Cobalt-60 treatment machine in the current vitro irradiation study. Thereafter, a micropipette-aspiration technique was used to measure the elastic… More >
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