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Search Results (19)
  • Open Access

    ARTICLE

    Minimally Invasive Congenital Cardiac Surgery: A Large Volume European Experience

    Alvise Guariento1,2, Ilias P. Doulamis3, David Blitzer4, Claudia Cattapan2, Massimo A. Padalino2, Vladimiro L. Vida2,*

    Congenital Heart Disease, Vol.15, No.3, pp. 127-139, 2020, DOI:10.32604/CHD.2020.012197 - 15 July 2020

    Abstract Background: In an effort to reduce postoperative trauma and achieve more cosmetic results, minimally invasive approaches to correct congenital heart anomalies have been recently proposed and increasingly adopted. Here we describe our experience for the past 23 years. Methods: Patients who underwent a surgical procedure between February 1996 and March 2019 with a minimally invasive approach for the correction of congenital heart disease in our center were included in this study. A statistical analysis was carried out to compare the results of the different minimally invasive techniques. A meta-analysis was conducted to compare our results in… More >

  • Open Access

    ARTICLE

    African-American men with prostate cancer have larger tumor volume than Caucasian men despite no difference in serum prostate specifc antigen

    Jay G. Fuletra1, Anastasiya Kamenko2, Frederick Ramsey3, Daniel D. Eun2, Adam C. Reese2

    Canadian Journal of Urology, Vol.25, No.1, pp. 9193-9198, 2018

    Abstract Introduction: Prior studies suggest that among men with low-grade prostate cancer, African American (AA) men produce less prostate-specific antigen (PSA) than Caucasians. We investigated racial differences in PSA, PSA density (PSAD), and tumor volume among men with prostate cancer, regardless of tumor grade. If present, these differences would suggest that AA men may benefit from different screening, surveillance, and treatment regimens compared to Caucasians.
    Materials and methods: We identified men from our institutional prostate cancer database who underwent radical prostatectomy between 2012 and 2015. Clinicopathologic parameters were compared by race. Multivariable linear regression was then performed to… More >

  • Open Access

    MEETING REVIEW

    Risks, benefits, and approaches to hormonal blockade in prostate cancer
    Highlights from the European Association of Urology Meeting, March 20-24, 2015, Madrid, Spain

    Jack Barkin

    Canadian Journal of Urology, Vol.22, No.3, pp. 7847-7852, 2015

    Abstract Several abstracts presented at the 2015 European Association of Urology Meeting highlighted new developments in hormone therapy for prostate cancer management. One abstract described how the luteinizing hormone-releasing hormone (LHRH)/gonadotropin-releasing hormone (GnRH) agonist leuprolide, but not the LHRH/GnRH antagonist degarelix, induced plaque instability in a mouse model. A second abstract showed that in patients with a history of severe cardiovascular disease, degarelix was associated with fewer cardiovascular events than treatment with an LHRH agonist. A third abstract showed how primary androgen-deprivation therapy was linked with increased all-cause mortality in a US registry. A fourth abstract More >

  • Open Access

    ARTICLE

    Overestimation of prostate cancer mortality and other-cause mortality by the Kaplan-Meier method

    Xiaoye Zhu, Ries Kranse, Meelan Bul, Chris H. Bangma, Fritz H. Schröder, Monique J. Roobol

    Canadian Journal of Urology, Vol.20, No.3, pp. 6756-6760, 2013

    Abstract Introduction: To assess the extent of overestimation of the cumulative probability of death by the Kaplan-Meier method with the competing-risks regression analysis as reference approach.
    Materials and methods: Data were derived from the screening arm of the Rotterdam branch of the European Randomized Study of Screening for Prostate Cancer (ERSPC). The screening arm consisted of 21210 men between the ages of 55 and 74 at study entry. Follow up concerning mortality was complete through 2008. Endpoints were 5 and 10 year cumulative probabilities of prostate cancer death and death from other causes. Relative bias was defined as… More >

  • Open Access

    MEETING REVIEW

    New fndings in bladder and prostate cancer: highlights from the 26th annual congress of the European Association of Urology,March 18-22, 2011, Vienna, Austria

    Alex Farr1, Roman Herout1, Markus Margreiter1, Georgi Tosev1, Bob Djavan2

    Canadian Journal of Urology, Vol.18, No.2, pp. 5601-5607, 2011

    Abstract At the recent annual congress, of the European Association of Urology (EAU), urologists from around the world presented their exciting discoveries related to an array of topics. Besides the huge variety of different sessions and courses, the EAU Section of Uro-Technology (ESUT) transmitted live broadcasts of surgeries from the medical universities of Vienna and Heilbronn, focusing on novel surgical techniques. Unfortunately, this year’s congress was clouded by the environmental disaster and nuclear accident in Japan, which prevented a number of Japanese urologists to attend the congress due to obstacles in travelling. In this brief update, More >

  • Open Access

    ARTICLE

    Behavior and preservation of an in vitro collection of European aspen in Spain

    M.T. MARTIN*, H.E. PEDRANZANI**, R. SIERRA DE GRADO

    BIOCELL, Vol.31, No.1, pp. 41-49, 2007, DOI:10.32604/biocell.2007.31.041

    Abstract An in vitro collection has been established with selected European aspen from Palencia province (Spain). Currently, this collection includes 32 high quality clones, selected for their good bearing and healthy state. Most of them belong to different discrete local populations.
    Populus tremula L. was propagated in proliferation Aspen Culture Medium; they required subculture every 3 months. The purpose of this study was, therefore, to select a medium which allows the maintenance of 32 clones for a period longer than 3 months without subculture and to observe the behavior of those clones in 15 different culture medium compositions. Seven… More >

  • Open Access

    ARTICLE

    Argentinean cultivars of Vitis vinifera grow better than european ones when cultured in vitro under salinity

    JUAN B. CAVAGNARO, MARÍA T. PONCE, JAVIER GUZMÁN, MIGUEL A. CIRRINCIONE

    BIOCELL, Vol.30, No.1, pp. 1-7, 2006, DOI:10.32604/biocell.2006.30.001

    Abstract Argentinean Vitis vinifera cultivars although originated from Europe, have clear ampelographic and genotypic differences as compared with the European cultivars currently used in wine making. In vitro evaluation of salt tolerance has been used in many species. Our hypothesis was that Argentinean cultivars are more tolerant to salinity than European ones. Three European cultivars, Malbec, Cabernet Sauvignon and Chardonnay and four Argentinean cultivars, Cereza, Criolla Chica, Pedro Gimenez and Torrontes Riojano were tested by in vitro culture. Treatments included: 1) Control, 2) 60 mEq/L of a mixture of three parts of NaCl and one part of CaCl2 and 3)… More >

  • Open Access

    ARTICLE

    The Solution Crystallisation Diagnostics Facility, a European Facility for Microgravity Research on Structures from Solutions on Board the ISS

    V. Pletser1, R. Bosch2, L. Potthast2, R. Kassel3

    FDMP-Fluid Dynamics & Materials Processing, Vol.2, No.1, pp. 65-76, 2006, DOI:10.3970/fdmp.2006.002.065

    Abstract Orbital weightless conditions have been shown to yield better and larger crystals. The Solution Crystallization Diagnostics Facility (SCDF) is a third generation instrument developed by ESA and dedicated to the observation and study with advanced diagnostics nucleation and crystallisation processes of molecules from solutions on board the International Space Station. The SCDF is intended to be used for studies of proteins and large biomolecules, and more generally of any kind of molecules growing from solutions, using the powerful set of diagnostics means available in the SCDF platform. Several protein crystallisation reactors have been developed to More >

  • Open Access

    ARTICLE

    Detection of prostate cancer: the impact of the European Randomized Study of Screening for Prostate Cancer (ERSPC)

    Fritz H. Schröder

    Canadian Journal of Urology, Vol.12, Suppl.1, pp. 2-6, 2005

    Abstract The European Randomized Study of Screening for Prostate Cancer (ERSPC) is a large, randomized controlled trial of screening versus control, conducted in eight European countries (Belgium, Finland, France, Italy, the Netherlands, Spain, Sweden, and Switzerland). This article focuses on important aspects relating to recent findings from the ERSPC about two topics: first, leadtime and overdiagnosis, and second, prostate-specific antigen (PSA) as a test for repeated screening.
    The ERSPC together with the prostate cancer arm of the Prostate, Lung, Colon and Ovary (PLCO) screening trial of the National Cancer Institute in the United States are set to… More >

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