M. Elisabeth Heal1, Lanier B. Jackson2, Andrew M. Atz2, Ryan J. Butts3
Congenital Heart Disease, Vol.12, No.4, pp. 399-402, 2017, DOI:10.1111/chd.12451
Abstract Cardiopulmonary exercise testing (CPET) aids in clinical assessment of patients with Fontan circulation.
Effects of persistent fenestration on CPET variables have not been clearly defined. Associations
between fenestration and CPET variables at anaerobic threshold (AT) and peak exercise were explored
in the Pediatric Heart Network Fontan Cross-Sectional Study cohort. Fenestration patency was associated with a greater decrease in oxygen saturation from rest to peak exercise (fenestration -4.9 ±
3.8 v. nonfenestration -3 ± 3.5; P < .001). Physiological dead space at peak exercise was higher in
fenestrated v. nonfenestrated (25.2 ± 16.1 v. 21.4 ± 15.2; P = .03). There… More >
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